Sodium pentaborate prevents acetaminophen-induced hepatorenal injury by suppressing oxidative stress, lipid peroxidation, apoptosis, and inflammatory cytokines in …

E Aktas Senocak, N Utlu, S Kurt, S Kucukler… - … Trace Element Research, 2024 - Springer
Abstract Acetaminophen (N-acetyl-p-aminophenol, APAP, or paracetamol) is one of the
drugs that may be damaging to the kidneys and liver when used in excess. In this context, it …

Antioxidant, hepatoprotective & nephroprotective potential of a novel synthetic compound 2′, 3′-dihydroxybenzylidene in paracetamol intoxicated rats

M Attaullah, A Ullah, M Hussain, M Zahoor, R Ullah… - Heliyon, 2023 - cell.com
Paracetamol is a commonly used analgesic and antipyretic drug, but at a high dose level, it
leads to deleterious side effects. The need to investigate new hepatoprotective drugs is …

Acute and subacute toxicity evaluation of hydroalcoholic extract of Caryota urens leaves in Wistar rats

S Balaji, KK Ganesan - Journal of Applied Pharmaceutical Science, 2020 - japsonline.com
Caryota urens native to Srilanka and India grows in tropical and subtropical regions. It is rich
in nutrition and show pharmacological properties owing to the presence of flavonoids …

MRI-based preclinical discovery of DILI: A lesson from paracetamol-induced hepatotoxicity

IP Grudzinski, M Ruzycka, A Cieszanowski… - Regulatory Toxicology …, 2019 - Elsevier
Worldwide, drug-induced liver injury (DILI) is a major cause of hepatic failure. It is also the
leading cause of withdrawal, cautionary labeling, and restricted usage of licensed drugs; …

[图书][B] Handbook of Research on Herbal Liver Protection: Hepatoprotective Plants

T Pullaiah, M Ramaiah - 2021 - taylorfrancis.com
This important volume provides a comprehensive overview of hepatotoxicity and medicinal
plants used for protecting the liver and for curing liver toxicity and liver diseases. To date …

Hepatoprotective and antioxidant properties of the methanol leaf extract of Diaphananthe bidens in acetaminophen-induced hepatotoxicity in rats

PE Aba, KO Ugwueze, SO Onoja… - Tropical Journal of …, 2019 - ajol.info
Purpose: To investigate the hepatoprotective and antioxidant properties of the methanol
extract of Diaphananthe bidens leaf using acetaminophen-induced hepatotoxicity rat model …

Tetrapleura tetraptera ethylacetate pod extract and its biochemical effects on acetaminophen-induced hepatotoxic female rat

EABA Patrick, AK Marie… - Notulae Scientia …, 2022 - search.proquest.com
The study investigated the effect of ethyl acetate pod extract of Tetrapleura tetrapteraon
biochemical markers of liver damage, in vivo and in vitro antioxidant properties using …

[PDF][PDF] Tetrapleura tetraptera ethylacetate pod extract and its biochemical effects on acetaminophen-induced hepatotoxic female rat.

PE Aba, MA Kalu, SC Udem - 2022 - mail.notulaebiologicae.ro
The study investigated the effect of ethyl acetate pod extract of Tetrapleura tetraptera on
biochemical markers of liver damage, in vivo and in vitro antioxidant properties using …

[PDF][PDF] AHC-08 methanol extract of Spondias mombin leaf protects the liver against acetaminophen-induced hepatotoxicity in albino rats

PE Aba, VU Omoja, NE Obioma… - Proc. 43rd Annual …, 2018 - researchgate.net
This study investigated the protective effect of Spondias mombin against acetaminophen-
induced hepatotoxicity. Thirty female albino rats assigned to six groups of five rats per group …

Isolation, Characterization of Active Constituent and Evaluation of Hepatoprotective Activity of Inula racemosa Hook. f. roots

V Kumar, H Singh, AK Mishra - Oriental Journal of Chemistry, 2021 - search.proquest.com
Ayurvedic literature claims that Inula racemosa Hook. f. roots are beneficial for the liver. The
study's aim was to test the hepatoprotective effect of Inula racemosa Hook. f. roots ethanolic …