Hydrogel microparticles for biomedical applications

AC Daly, L Riley, T Segura, JA Burdick - Nature Reviews Materials, 2020 - nature.com
Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

Biomimetic anisotropic hydrogels: Advanced fabrication strategies, extraordinary functionalities, and broad applications

MTI Mredha, I Jeon - Progress in Materials Science, 2022 - Elsevier
A variety of soft, hydrogel-like materials with sophisticated micro-and nanoengineered
ordered structures that offer excellent functionalities exist in nature. Conventional synthetic …

[HTML][HTML] A reactive oxygen species-responsive hydrogel encapsulated with bone marrow derived stem cells promotes repair and regeneration of spinal cord injury

Z Li, T Zhao, J Ding, H Gu, Q Wang, Y Wang, D Zhang… - Bioactive materials, 2023 - Elsevier
Spinal cord injury (SCI) is an overwhelming and incurable disabling event accompanied by
complicated inflammation-related pathological processes, such as excessive reactive …

[HTML][HTML] Microgel assembly: Fabrication, characteristics and application in tissue engineering and regenerative medicine

Q Feng, D Li, Q Li, X Cao, H Dong - Bioactive materials, 2022 - Elsevier
Microgel assembly, a macroscopic aggregate formed by bottom-up assembly of microgels, is
now emerging as prospective biomaterials for applications in tissue engineering and …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Guiding lights: tissue bioprinting using photoactivated materials

M Lee, R Rizzo, F Surman, M Zenobi-Wong - Chemical Reviews, 2020 - ACS Publications
Photoactivated materials have found widespread use in biological and medical applications
and are playing an increasingly important role in the nascent field of three-dimensional (3D) …

Restoration of spinal cord biophysical microenvironment for enhancing tissue repair by injury-responsive smart hydrogel

C Fan, W Yang, L Zhang, H Cai, Y Zhuang, Y Chen… - Biomaterials, 2022 - Elsevier
Spinal cord injury (SCI) represents a central nervous system disaster, resulting in the
destruction of spinal cord structure and function and the formation of an adverse …

Regenerative therapies for spinal cord injury

N Ashammakhi, HJ Kim, A Ehsanipour… - … Engineering Part B …, 2019 - liebertpub.com
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …

Nerve growth factor-laden anisotropic silk nanofiber hydrogels to regulate neuronal/astroglial differentiation for scarless spinal cord repair

X Gao, W Cheng, X Zhang, Z Zhou, Z Ding… - … Applied Materials & …, 2022 - ACS Publications
Scarless spinal cord regeneration remains a challenge due to the complicated
microenvironment at lesion sites. In this study, the nerve growth factor (NGF) was …

3D gelatin microsphere scaffolds promote functional recovery after spinal cord hemisection in rats

H Ke, H Yang, Y Zhao, T Li, D Xin, C Gai… - Advanced …, 2023 - Wiley Online Library
Spinal cord injury (SCI) damages signal connections and conductions, with the result that
neuronal circuits are disrupted leading to neural dysfunctions. Such injuries represent a …