Dissecting redox biology using fluorescent protein sensors
Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …
The incomplete glutathione puzzle: just guessing at numbers and figures?
M Deponte - Antioxidants & redox signaling, 2017 - liebertpub.com
Significance: Glutathione metabolism is comparable to a jigsaw puzzle with too many
pieces. It is supposed to comprise (i) the reduction of disulfides, hydroperoxides, sulfenic …
pieces. It is supposed to comprise (i) the reduction of disulfides, hydroperoxides, sulfenic …
Parallel molecular mechanisms for enzyme temperature adaptation
INTRODUCTION Over billions of years, organisms and their enzymes have been evolving
and adapting in response to selection pressures from their environments. In particular …
and adapting in response to selection pressures from their environments. In particular …
Regulation of mitochondrial hydrogen peroxide availability by protein S-glutathionylation
RJ Mailloux, C Grayson, O Koufos - Cells, 2022 - mdpi.com
Background: It has been four decades since protein S-glutathionylation was proposed to
serve as a regulator of cell metabolism. Since then, this redox-sensitive covalent …
serve as a regulator of cell metabolism. Since then, this redox-sensitive covalent …
Role of protein S-Glutathionylation in cancer progression and development of resistance to anti-cancer drugs
The survival, functioning and proliferation of mammalian cells are highly dependent on the
cellular response and adaptation to changes in their redox environment. Cancer cells often …
cellular response and adaptation to changes in their redox environment. Cancer cells often …
Physiological associations between vitamin B deficiency and diabetic kidney disease
HHL Wu, T McDonnell, R Chinnadurai - Biomedicines, 2023 - mdpi.com
The number of people living with chronic kidney disease (CKD) is growing as our global
population continues to expand. With aging, diabetes, and cardiovascular disease being …
population continues to expand. With aging, diabetes, and cardiovascular disease being …
Estimation of early postmortem interval through biochemical and pathological changes in rat heart and kidney
Accurate estimation of time passed since death is a complicated task in forensic medicine
especially in homicide or unwitnessed death investigations. Changes in oxidant/antioxidant …
especially in homicide or unwitnessed death investigations. Changes in oxidant/antioxidant …
Purification of rat kidney glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase enzymes using 2′, 5′-ADP …
The enzymes of glucose 6-phosphate dehydrogenase (G6PD), 6-phosphogluconate
dehydrogenase (6PGD), and glutathione reductase (GR) were purified from rat kidney in …
dehydrogenase (6PGD), and glutathione reductase (GR) were purified from rat kidney in …
Acute and sub-acute bisphenol-B exposures adversely affect sperm count and quality in adolescent male mice
Abstract Bisphenol-B (BPB), an analogue of bisphenol-A is used in the plastic industry. It has
been found to leach from plastic containers leading to its contamination in canned food …
been found to leach from plastic containers leading to its contamination in canned food …
NOX-like ROS production by glutathione reductase
JM Diaz, X Shi - Iscience, 2022 - cell.com
In organisms from bacteria to mammals, NADPH oxidase (NOX) catalyzes the production of
beneficial reactive oxygen species (ROS) such as superoxide (O 2−). However, our previous …
beneficial reactive oxygen species (ROS) such as superoxide (O 2−). However, our previous …