The mechanisms underlying innate immune memory have been extensively explored in the
last decades but are in fact largely unknown. Although the specificity of adaptive immune …

Traditionally, the innate and adaptive immune systems are differentiated by their specificity
and memory capacity. In recent years, however, this paradigm has shifted: Cells of the …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Background We now know that depression is associated with a chronic, low-grade
inflammatory response and activation of cell-mediated immunity, as well as activation of the …

Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Abstract Electronic-cigarettes (e-cigs) represent a significant and increasing proportion of
tobacco product consumption, which may pose an oral health concern. Oxidative/carbonyl …

Periodontal disease (PD), or periodontitis, is defined as a bacterially induced disease of the
tooth‐supporting (periodontal) tissues. It is characterized by inflammation and bone loss; …

Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …

This introductory article examines the potential mechanisms that may play a role in the
associations between periodontitis and the systemic conditions being considered in the …

Gingival fibroblasts (GFs) are essential components of the periodontium, which are
responsible for the maintenance of tissue structure and integrity. However, the physiological …