Electrochemical imaging of cells and tissues

TE Lin, S Rapino, HH Girault, A Lesch - Chemical science, 2018 - pubs.rsc.org
The technological and experimental progress in electrochemical imaging of biological
specimens is discussed with a view on potential applications for skin cancer diagnostics …

Recent advances in electrochemiluminescence-based systems for mammalian cell analysis

K Hiramoto, E Villani, T Iwama, K Komatsu, S Inagi… - Micromachines, 2020 - mdpi.com
Mammalian cell analysis is essential in the context of both fundamental studies and clinical
applications. Among the various techniques available for cell analysis …

PEDOT: PSS hydrogels with high conductivity and biocompatibility for in situ cell sensing

T Yang, M Yang, C Xu, K Yang, Y Su, Y Ye… - Journal of Materials …, 2023 - pubs.rsc.org
Conducting polymer hydrogels, especially poly (3, 4-ethylenedioxythiophene): poly (styrene
sulfonate)(PEDOT: PSS) hydrogels, show great promise in soft bioelectronics due to their …

Oxygen consumption rate of tumour spheroids during necrotic-like core formation

R Mukomoto, Y Nashimoto, T Terai, T Imaizumi… - Analyst, 2020 - pubs.rsc.org
Hypoxia is one of the major hallmarks of solid tumours and is associated with the poor
prognosis of various cancers. A multicellular aggregate, termed a spheroid, has been used …

Closed bipolar electrode array for on-chip analysis of cellular respiration by cell aggregates

K Ino, R Yaegaki, K Hiramoto, Y Nashimoto… - ACS …, 2020 - ACS Publications
Cell aggregates have attracted much attention owing to their potential applications in tissue
engineering and drug screening. To evaluate cellular respiration of individual cell …

Bioprinting-based automated deposition of single cancer cell spheroids into oxygen sensor microelectrode wells

J Dornhof, V Zieger, J Kieninger, D Frejek, R Zengerle… - Lab on a Chip, 2022 - pubs.rsc.org
Three-dimensional (3D) cell agglomerates, such as microtissues, organoids, and spheroids,
become increasingly relevant in biomedicine. They can provide in vitro models that …

Electrochemiluminescence imaging of respiratory activity of cellular spheroids using sequential potential steps

K Hiramoto, K Ino, K Komatsu, Y Nashimoto… - Biosensors and …, 2021 - Elsevier
The respiratory activity of cultured cells can be electrochemically monitored using scanning
electrochemical microscopy (SECM) with high spatial resolution. However, in SECM, the …

Fabrication of high-density vertical closed bipolar electrode arrays by carbon paste filling method for two-dimensional chemical imaging

T Iwama, KY Inoue, H Shiku - Analytical Chemistry, 2022 - ACS Publications
In this study, a carbon paste filling method was proposed as a simple strategy for fabricating
high-density bipolar electrode (BPE) arrays for bipolar electrochemical microscopy (BEM) …

Electrochemiluminescence imaging of cellular adhesion in vascular endothelial cells during tube formation on hydrogel scaffolds

K Ino, K Komatsu, K Hiramoto, Y Utagawa… - Electrochimica …, 2022 - Elsevier
This study describes a method for electrochemiluminescence (ECL) imaging of cellular
adhesion in vascular endothelial cells during tube formation on hydrogel scaffolds. Human …

Bioimaging using bipolar electrochemical microscopy with improved spatial resolution

T Iwama, KY Inoue, H Abe, T Matsue, H Shiku - Analyst, 2020 - pubs.rsc.org
In this study, we developed bipolar electrochemical microscopy (BEM) using a closed
bipolar electrode (cBPE) array with an electrochemiluminescence (ECL) detecting system …