The great success of cisplatin as a chemotherapeutic agent considerably increased
research efforts in inorganic biochemistry to identify more metallic drugs having the potential …

To develop the next-generation Pt drug with remarkable activity and low toxicity to maximally
inhibit tumor growth, we optimized a Pt (II) thiosemicarbazone compound (C4) with …

Topoisomerases, common targets for anti-cancer therapeutics, are crucial enzymes for DNA
replication, transcription, and many other aspects of DNA metabolism. The potential anti …

Simple Summary Besides zinc, also iron and copper need to be considered to play a role in
the mode of action and resistance development of the anticancer thiosemicarbazone COTI-2 …

To develop the next-generation metal agents for efficiently inhibiting tumor growth, a series
of novel mononuclear, binuclear and trinuclear copper (Cu) thiophene-2-formaldehyde …

This paper deals with the biological properties of 14 coordination complexes assembled
from a large panel of thiosemicarbazone ligands and [Mo 2 O 2 S 2] 2+ cluster. The …

This paper deals with the synthesis, structural studies, and behavior in solution of
unprecedented coordination complexes built by the association of a panel of 14 …

[MoV2O2S2] 2+-based thiosemicarbazone complexes appear as very promising molecules
for biological applications due to the intrinsic properties of their components. This paper …

The structure assignment and conformational analysis of thiosemicarbazone KKI15 and
thiocarbohydrazone KKI18 were performed through homonuclear and heteronuclear 2D …

To treat cancer and inhibit its metastasis to the greatest extent, we proposed to develop an
Au (III) agent to induce immunogenic cell death (ICD) and establish long-term immunity. To …