Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond
Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …
globe. Candida species are among the most common causes of invasive mycotic disease …
Biofilm of Candida albicans: formation, regulation and resistance
R Pereira, RO Dos Santos Fontenelle… - Journal of Applied …, 2021 - academic.oup.com
Candida albicans is the most common human fungal pathogen, causing infections that
range from mucous membranes to systemic infections. The present article provides an …
range from mucous membranes to systemic infections. The present article provides an …
Candida albicans biofilms and polymicrobial interactions
Candida albicans is a common fungus of the human microbiota. While generally a harmless
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …
commensal in healthy individuals, several factors can lead to its overgrowth and cause a …
Development and regulation of single- and multi-species Candida albicans biofilms
MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …
[HTML][HTML] Candida albicans biofilms: development, regulation, and molecular mechanisms
A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …
Candida albicans Biofilms and Human Disease
CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …
Candida parapsilosis: from genes to the bedside
R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Antifungal therapy: new advances in the understanding and treatment of mycosis
L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
Pathogenesis of Candida albicans biofilm
C Tsui, EF Kong, MA Jabra-Rizk - FEMS Pathogens and …, 2016 - academic.oup.com
Candida albicans is the most common human fungal pathogen causing diseases ranging
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …
from mucosal to systemic infections. As a commensal, C. albicans asymptomatically …
Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …