Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
B Nilius, A Szallasi - Pharmacological reviews, 2014 - ASPET
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
The bioactivity and toxicological actions of carvacrol
ZE Suntres, J Coccimiglio, M Alipour - Critical reviews in food …, 2015 - Taylor & Francis
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants,
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …
including thyme and oregano. Presently, carvacrol is used in low concentrations as a food …
Transient receptor potential (TRP) channels: a clinical perspective
Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
Plant volatiles: production, function and pharmacology
Covering: 1989 to February 2011 Plant volatiles typically occur as a complex mixture of low-
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …
Pesticidal activity and mode of action of monoterpenes
Z Liu, QX Li, B Song - Journal of Agricultural and Food Chemistry, 2022 - ACS Publications
Synthetic pesticides are often associated with issues such as pest resistance, persistent
residue, nontarget toxicity, and environmental issues. Therefore, the research and …
residue, nontarget toxicity, and environmental issues. Therefore, the research and …
TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals
RK Adapala, RJ Thoppil, DJ Luther, S Paruchuri… - Journal of molecular and …, 2013 - Elsevier
The phenotypic switch underlying the differentiation of cardiac fibroblasts into
hypersecretory myofibroblasts is critical for cardiac remodeling following myocardial …
hypersecretory myofibroblasts is critical for cardiac remodeling following myocardial …
Carvacrol attenuates mechanical hypernociception and inflammatory response
AG Guimarães, MA Xavier, MT de Santana… - Naunyn-Schmiedeberg's …, 2012 - Springer
Carvacrol is a phenolic monoterpene present in the essential oil of the family Lamiaceae, as
in the genera Origanum and Thymus. We previously reported that carvacrol is effective as an …
in the genera Origanum and Thymus. We previously reported that carvacrol is effective as an …
Toxicity and neurophysiological impacts of plant essential oil components on bed bugs (Cimicidae: Hemiptera)
Bed bugs (Cimex lectularius L.) are globally important human parasites. Integrated pest
management (IPM) approaches, which include the use of essential oil-based insecticidal …
management (IPM) approaches, which include the use of essential oil-based insecticidal …
Encapsulation of carvacrol, a monoterpene present in the essential oil of oregano, with β-cyclodextrin, improves the pharmacological response on cancer pain …
AG Guimarães, MA Oliveira, R dos Santos Alves… - Chemico-biological …, 2015 - Elsevier
Cancer pain is a major public health problem worldwide due to the strong impact on the
quality of life of patients and side effects of the existing therapeutic options. Monoterpenes …
quality of life of patients and side effects of the existing therapeutic options. Monoterpenes …