HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

Preventive and therapeutic strategies for bovine leukemia virus: lessons for HTLV

SM Rodríguez, A Florins, N Gillet, A De Brogniez… - Viruses, 2011 - mdpi.com
Bovine leukemia virus (BLV) is a retrovirus closely related to the human T-lymphotropic virus
type 1 (HTLV-1). BLV is a major animal health problem worldwide causing important …

Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy

M Matsuoka, KT Jeang - Oncogene, 2011 - nature.com
The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …

[HTML][HTML] HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

Inflammatory manifestations of HTLV-1 and their therapeutic options

F Martin, GP Taylor, S Jacobson - Expert review of clinical …, 2014 - Taylor & Francis
Human T lymphotropic virus type 1 (HTLV-1) is one of the most intriguing retroviruses
infecting humans. Most commonly, infection remains undetected, since it does not cause …

[HTML][HTML] Recent advances in BLV research

PY Barez, A De Brogniez, A Carpentier, H Gazon… - Viruses, 2015 - mdpi.com
Different animal models have been proposed to investigate the mechanisms of Human T-
lymphotropic Virus (HTLV)-induced pathogenesis: rats, transgenic and NOD-SCID/γcnull …

Tropical spastic paraparesis and HTLV-1 associated myelopathy: clinical, epidemiological, virological and therapeutic aspects

A Gessain, R Mahieux - Revue neurologique, 2012 - Elsevier
In 1980, HumanT cell leukemia/lymphoma virus type 1 (HTLV-1) was the first oncogenic
human retrovirus to be discovered. HTLV-1 belongs to the Retroviridae family, the …

[HTML][HTML] HTLV-1: persistence and pathogenesis

LB Cook, M Elemans, AG Rowan, B Asquith - Virology, 2013 - Elsevier
► General method to identify the determinants of protective immunity and its application to
HTLV-1.► Observation made that “innate” KIR receptors enhance the HLA class I-restricted …

[HTML][HTML] Massive depletion of bovine leukemia virus proviral clones located in genomic transcriptionally active sites during primary infection

NA Gillet, G Gutiérrez, SM Rodriguez… - PLoS …, 2013 - journals.plos.org
Deltaretroviruses such as human T-lymphotropic virus type 1 (HTLV-1) and bovine leukemia
virus (BLV) induce a persistent infection that remains generally asymptomatic but can also …

[HTML][HTML] Molecular studies of HTLV-1 replication: an update

JL Martin, JO Maldonado, JD Mueller, W Zhang… - Viruses, 2016 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) was the first human retrovirus discovered.
Studies on HTLV-1 have been instrumental for our understanding of the molecular …