[HTML][HTML] Interaction of 6 mercaptopurine with calf thymus DNA–deciphering the binding mode and photoinduced DNA damage

SU Rehman, Z Yaseen, MA Husain, T Sarwar… - PLoS one, 2014 - journals.plos.org
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic
drugs. Elucidating the binding between small molecules and DNA provides great help in …

Multi-spectroscopic and molecular modelling studies on the interaction of esculetin with calf thymus DNA

T Sarwar, MA Husain, SU Rehman, HM Ishqi… - Molecular …, 2015 - pubs.rsc.org
Understanding the interaction of small molecules with DNA has become an active research
area at the interface between chemistry, molecular biology and medicine. Plant derived …

Interaction of coumarin with calf thymus DNA: deciphering the mode of binding by in vitro studies

T Sarwar, SU Rehman, MA Husain, HM Ishqi… - International journal of …, 2015 - Elsevier
DNA is the major target for a wide range of therapeutic substances. Thus, there has been
considerable interest in the binding studies of small molecules with DNA. Interaction …

Interaction of capsaicin with calf thymus DNA: A multi-spectroscopic and molecular modelling study

FA Qais, KM Abdullah, MM Alam, I Naseem… - International journal of …, 2017 - Elsevier
Studying the mode of interaction between small molecules and DNA has received much
attention in recent years, as many drugs have been reported to directly interact with DNA …

Carbon dots with red emission as a fluorescent and colorimeteric dual-readout probe for the detection of chromium (vi) and cysteine and its logic gate operation

Y Gao, Y Jiao, W Lu, Y Liu, H Han, X Gong… - Journal of Materials …, 2018 - pubs.rsc.org
A novel visual probe with red fluorescent carbon dots (CDs) has been facilely fabricated for
the sequential detection of chromium (VI)[Cr (VI)] and cysteine (Cys) via a fluorescent and …

Carbon nano-dots as a fluorescent and colorimetric dual-readout probe for the detection of arginine and Cu 2+ and its logic gate operation

W Lu, Y Gao, Y Jiao, S Shuang, C Li, C Dong - Nanoscale, 2017 - pubs.rsc.org
A new visual fluorescent probe based on carbon nano-dots (CNDs) has been facilely
synthesized via one step microwave-assisted pyrolysis and utilized for sequential detection …

Synthesis and biological evaluation of 1-phenyl-4, 6-dihydrobenzo [b] pyrazolo [3, 4-d] azepin-5 (1H)-one/thiones as anticancer agents

R Parupalli, R Akunuri, A Spandana… - Bioorganic …, 2023 - Elsevier
Cancer is associated with uncontrolled cell proliferation invading adjoining tissues and
organs. Despite the availability of several chemotherapeutic agents, the constant search for …

Caffeic acid binds to the minor groove of calf thymus DNA: A multi-spectroscopic, thermodynamics and molecular modelling study

T Sarwar, HM Ishqi, SU Rehman, MA Husain… - International journal of …, 2017 - Elsevier
Caffeic acid (CA) is a plant polyphenol which acts as an antioxidant and has various
pharmacological effects. DNA is one of the major cellular targets of therapeutic molecules …

In vitro DNA binding studies of therapeutic and prophylactic drug citral

MF Alam, S Varshney, MA Khan, AA Laskar… - International journal of …, 2018 - Elsevier
The study of drug-DNA interactions is of great importance, as it paves the way towards the
design of better therapeutic agents. Here, the interaction of DNA with a therapeutic and …

[HTML][HTML] Platinum (II) terpyridine anticancer complexes possessing multiple mode of DNA interaction and EGFR inhibiting activity

C Li, F Xu, Y Zhao, W Zheng, W Zeng, Q Luo… - Frontiers in …, 2020 - frontiersin.org
Platinum (II) terpyridine complexes has attracted increasing attention as they have displayed
great potential as antitumor agents due to their high intercalation affinity with nucleic acids …