Dendritic cells function in the immune system to instruct adaptive immune cells to respond
accordingly to different threats. While conventional dendritic cells can be subdivided into two …

Classical dendritic cells (cDCs) are mononuclear phagocytes of hematopoietic origin
specialized in the induction and regulation of adaptive immunity. Initially defined by their …

Lipid nanoparticle (LNP)-encapsulated mRNAs have emerged as effective vaccination tools
to stimulate immunity. The most common application of this technology is to deliver mRNAs …

Monocytes are abundant immune cells that infiltrate inflamed organs. However, the majority
of monocyte studies focus on circulating cells, rather than those in tissue. Here, we identify …

Immunoproteasome-reprogrammed mesenchymal stromal cells (IRMs) can surpass
dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination …

Dendritic cell (DC) populations are the orchestrators of immune responses and arise from
hematopoietic progenitors. Studies to unravel DC ontogeny have been conducted mainly in …

Dendritic cells (DCs) are mononuclear phagocytes of hematopoietic origin residing in
lymphoid and nonlymphoid tissues. DCs are often referred as the sentinels of the immune …

Designed protein agonists can enhance the efficiency of endogenous signaling pathways,
and provide a powerful means to control cellular functions and develop disease …

Innate immune cells can be found in all tissues of the body, where they play key roles both in
maintaining homeostasis and rapidly responding to challenges through use of their germline …