Role of pyroptosis in cardiovascular disease
Z Zhaolin, L Guohua, W Shiyuan, W Zuo - Cell proliferation, 2019 - Wiley Online Library
Cardiac function is determined by the dynamic equilibrium of various cell types and the
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …
[HTML][HTML] Mitochondrial calcium transport and the redox nature of the calcium-induced membrane permeability transition
Mitochondria possess a Ca 2+ transport system composed of separate Ca 2+ influx and
efflux pathways. Intramitochondrial Ca 2+ concentrations regulate oxidative …
efflux pathways. Intramitochondrial Ca 2+ concentrations regulate oxidative …
[HTML][HTML] SIRT3-mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia/reperfusion injury
Z Wang, R Sun, G Wang, Z Chen, Y Li, Y Zhao, D Liu… - Redox biology, 2020 - Elsevier
Abstract Background Hydrogen peroxide (H 2 O 2)-induced mitochondrial oxidative damage
is critical to intestinal ischemia/reperfusion (I/R) injury, and PRDX3 is an efficient H 2 O 2 …
is critical to intestinal ischemia/reperfusion (I/R) injury, and PRDX3 is an efficient H 2 O 2 …
Allicin decreases lipopolysaccharide-induced oxidative stress and inflammation in human umbilical vein endothelial cells through suppression of mitochondrial …
M Zhang, H Pan, Y Xu, X Wang, Z Qiu… - Cellular Physiology and …, 2017 - karger.com
Background: Allicin, a major component of garlic, is regarded as a cardioprotective agent
and is associated with increased endothelial function. Methods: The effects of allicin on …
and is associated with increased endothelial function. Methods: The effects of allicin on …
A dual Keap1 and p47phox inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis
ZC Wang, KM Niu, YJ Wu, KR Du, LW Qi, YB Zhou… - Cell death & …, 2022 - nature.com
Oxidative stress is a vital contributor to the development and progression of diabetes-
accelerated atherosclerosis. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a well-known …
accelerated atherosclerosis. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a well-known …
[Retracted] Puerarin Attenuates LPS‐Induced Inflammatory Responses and Oxidative Stress Injury in Human Umbilical Vein Endothelial Cells through Mitochondrial …
X Chang, T Zhang, D Liu, Q Meng… - Oxidative Medicine …, 2021 - Wiley Online Library
Atherosclerosis is closely associated with the inflammatory reaction of vascular endothelial
cells. Puerarin (Pue), the main active component isolated from the rhizome of Pueraria …
cells. Puerarin (Pue), the main active component isolated from the rhizome of Pueraria …
Targeting mitochondrial function in macrophages: A novel treatment strategy for atherosclerotic cardiovascular disease?
PH Becker, P Thérond, P Gaignard - Pharmacology & Therapeutics, 2023 - Elsevier
Atherosclerotic cardiovascular disease is a major cause of morbidity and mortality due to
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …
chronic arterial injury caused by hyperlipidemia, hypertension, inflammation and oxidative …
Endothelial dysfunction in neuroprogressive disorders—causes and suggested treatments
Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …
mitochondrial dysfunction may drive the development of endothelial dysfunction and …
Activating the PGC‐1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications …
Y Zhang, C Wang, Y Jin, Q Yang… - Oxidative medicine …, 2018 - Wiley Online Library
Catalpol, an iridoid glucoside, has been found present in large quantities in the root of
Rehmannia glutinosa L. and showed a strong antioxidant capacity in the previous study. In …
Rehmannia glutinosa L. and showed a strong antioxidant capacity in the previous study. In …
Mitochondrial bioenergetics and redox dysfunctions in hypercholesterolemia and atherosclerosis
HCF Oliveira, AE Vercesi - Molecular aspects of medicine, 2020 - Elsevier
In the first part of this review, we summarize basic mitochondrial bioenergetics concepts
showing that mitochondria are critical regulators of cell life and death. Until a few decades …
showing that mitochondria are critical regulators of cell life and death. Until a few decades …