The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting
The impact of physical and chemical modifications of nanoparticles on their biological
function has been systemically investigated and exploited to improve their circulation and …
function has been systemically investigated and exploited to improve their circulation and …
Designing drug delivery systems for cell therapy
Cell therapies, such as immune cell and stem cell therapies, are being preclinically and
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
clinically explored for the treatment of various diseases, but are often limited by low efficacy …
Materials for cell surface engineering
Cell therapies are emerging as a promising new therapeutic modality in medicine,
generating effective treatments for previously incurable diseases. Clinical success of cell …
generating effective treatments for previously incurable diseases. Clinical success of cell …
Biodegradable protein-based rockets for drug transportation and light-triggered release
We describe a biodegradable, self-propelled bovine serum albumin/poly-l-lysine (PLL/BSA)
multilayer rocket as a smart vehicle for efficient anticancer drug encapsulation/delivery to …
multilayer rocket as a smart vehicle for efficient anticancer drug encapsulation/delivery to …
Gold-nanoshell-functionalized polymer nanoswimmer for photomechanical poration of single-cell membrane
We report an ultrasound-driven gold-nanoshell-functionalized polymer multilayer tubular
nanoswimmer that can photomechanically perforate the membrane of a cancer cell by …
nanoswimmer that can photomechanically perforate the membrane of a cancer cell by …
Nanoparticles in polyelectrolyte multilayer layer-by-layer (LbL) films and capsules—key enabling components of hybrid coatings
Originally regarded as auxiliary additives, nanoparticles have become important
constituents of polyelectrolyte multilayers. They represent the key components to enhance …
constituents of polyelectrolyte multilayers. They represent the key components to enhance …
Cell–drug conjugates
Y Wang, J Shi, M Xin, AR Kahkoska, J Wang… - Nature Biomedical …, 2024 - nature.com
By combining living cells with therapeutics, cell–drug conjugates can potentiate the
functions of both components, particularly for applications in drug delivery and therapy. The …
functions of both components, particularly for applications in drug delivery and therapy. The …
Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation
Targeted delivery of drugs and imaging agents to inflamed tissues, as in the cases of cancer,
Alzheimer's disease, Parkinson's disease, and arthritis, represents one of the major …
Alzheimer's disease, Parkinson's disease, and arthritis, represents one of the major …