Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Lithium (Li+) is a first option treatment for adult acute episodes of Bipolar Disorder (BD) and
for the prophylaxis of new depressed or manic episodes. It is also the preferred choice as …

Background Bipolar disorder (BD) is associated with cortical and subcortical structural brain
abnormalities. It is unclear whether such alterations progressively change over time, and …

Cross-sectional neuroimaging studies show that bipolar disorder is associated with
structural brain abnormalities, predominantly observed in prefrontal and temporal cortex …

Background An increasing number of neuroimaging studies report alterations of cortical
thickness (CT) related to the neuropathology of bipolar disorder (BD). We provide here a …

Background: The literature on grey-matter volume alterations in bipolar disorder is
heterogeneous in its findings. Methods: Using effect-size differential mapping, we conducted …

Introduction Lithium treatment is considered the gold standard for the long-term
management of bipolar disorder and recurrent unipolar depression. It is also extremely …

Background Bipolar disorder (BD) is a highly heritable psychiatric disorder characterized by
episodes of manic and depressed mood states and associated with cortical brain …

Bipolar disorder is a lifelong challenge--but it doesn't have to rule your life. Find the science-
based information you need in the revised third edition of this indispensable guide. Trusted …

Objectives Despite the growing numbers and proportion of older adults with bipolar disorder
(OABD), there are very limited guidelines for the use of lithium with its double‐edged …