In this review article, we will describe the recent advances made towards understanding the
molecular and cell biological mechanisms of electrical synapse formation. New evidence …

Epithelial tissue responds rapidly to environmental triggers and is constantly renewed. This
tissue is also highly accessible for therapeutic targeting. This review highlights the role of …

Genes that are primarily expressed in cochlear glia-like supporting cells (GLSs) have not
been clearly associated with progressive deafness. Herein, we present a deafness locus …

One of the most common forms of genetic deafness has been predominantly associated with
pathogenic variants in the GJB2 gene, encoding transmembrane protein connexin 26 …

Connexin is a transmembrane protein present on the cell membrane of most cell types.
Connexins assemble into a hexameric hemichannel known as connexon that pairs with …

Cingulin, a cytoplasmic element of tight junctions (TJs), is involved in maintenance of the
integrity of epithelial and endothelial cells. However, the role of cingulin in the development …

Connexins (Cxs) are ubiquitous membrane proteins that are found throughout vertebrate
organs, acting as building blocks of the gap junctions (GJs) known to play vital roles in the …

Allergen recognition and processing by antigen presenting cells is essential for the
sensitization step of food allergy. Macrophages and dendritic cells are both phagocytic …

Cell junctions, including anchoring, occluding and communicating junctions, play an
indispensable role in the structural and functional organization of multicellular tissues …

Disabled-1 (Dab1) protein is an intracellular adaptor of reelin signaling required for prenatal
neuronal migration, as well as postnatal neurotransmission, memory formation and synaptic …