Endosomes are dynamic intracellular compartments that control the sorting of a constant
stream of different transmembrane cargos either for ESCRT‐mediated degradation or for …

The tubular endolysosomal network is a quality control system that ensures the proper
delivery of internalized receptors to specific subcellular destinations in order to maintain …

The Commander complex is required for endosomal recycling of diverse transmembrane
cargos and is mutated in Ritscher-Schinzel syndrome. It comprises two sub-assemblies …

The recycling of membrane proteins from endosomes to the cell surface is vital for cell
signaling and survival. Retriever, a trimeric complex of vacuolar protein-sorting-associated …

The retromer complex has a well-established role in endosomal protein sorting, being
necessary for maintaining the dynamic localisation of hundreds of membrane proteins that …

Endocytic recycling of internalized transmembrane proteins is essential for many important
physiological processes. Recent studies have revealed that retromer-related Sorting Nexin …

Legionella pneumophila promotes its survival and replication in phagocytes by actively
modulating cellular processes using effectors injected into host cells by its Dot/Icm type IV …

To prevail in the interaction with eukaryotic hosts, many bacterial pathogens use protein
secretion systems to release virulence factors at the host–pathogen interface and/or deliver …

Emergence of new viral agents is driven by evolution of interactions between viral proteins
and host targets. For instance, increased infectivity of SARS-CoV-2 compared to SARS-CoV …

Pontocerebellar hypoplasia (PCH) is a group of rare neurodevelopmental disorders with
limited diagnostic and therapeutic options. Mutations in WDR11, a subunit of the FAM91A1 …