An updated review of folate-functionalized nanocarriers: A promising ligand in cancer
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …
introduction of new nanotechnology-based drug delivery systems and the use of targeted …
Prodrug and nanomedicine approaches for the delivery of the camptothecin analogue SN38
Abstract SN38 (7-ethyl-10-hydroxy camptothecin) is a prominent and efficacious anticancer
agent. It is poorly soluble in both water and pharmaceutically approved solvents; therefore …
agent. It is poorly soluble in both water and pharmaceutically approved solvents; therefore …
[HTML][HTML] Polymeric nanocarriers: A promising tool for early diagnosis and efficient treatment of colorectal cancer
Background Colorectal cancer (CRC) is the third most prevalent type of cancer for incidence
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …
and second for mortality worldwide. Late diagnosis and inconvenient and expensive current …
Targeted delivery and controlled release of doxorubicin to cancer cells by smart ATP-responsive Y-shaped DNA structure-capped mesoporous silica nanoparticles
In this study, a dual-receptor doxorubicin-targeted delivery system based on mesoporous
silica nanoparticles (MSNs) modified with mucine-1 and ATP aptamers (DOX@ MSNs-Apts) …
silica nanoparticles (MSNs) modified with mucine-1 and ATP aptamers (DOX@ MSNs-Apts) …
Research progress of SN38 drug delivery system in cancer treatment
Q Qi, H Tian, B Yue, B Zhai, F Zhao - International Journal of …, 2024 - Taylor & Francis
The active metabolite of irinotecan (CPT-11), 7-ethyl-10-hydroxycamptothecin (SN38), is
100–1000 times more active than CPT-11 and has shown inhibitory effects on a range of …
100–1000 times more active than CPT-11 and has shown inhibitory effects on a range of …
Targeted MMP-2 responsive chimeric polymersomes for therapy against colorectal cancer
In the current study, polyethylene glycol (PEG) was linked to polylactide (PLA) through the
synthetic peptide PVGLIG which can be selectively cleaved by the tumor-associated matrix …
synthetic peptide PVGLIG which can be selectively cleaved by the tumor-associated matrix …
Targeting of nanoparticles in cancer: drug delivery and diagnostics
Anticancer agents continue to be a preferred therapeutic option for several malignancies.
Despite their effectiveness, oncologists are continually looking for tumor-specific anticancer …
Despite their effectiveness, oncologists are continually looking for tumor-specific anticancer …
Nanoparticle delivery of natural products in the prevention and treatment of cancers: current status and future prospects
The advent of nanotechnology has had a revolutionary impact on many aspects of 21st
century life. Nanotechnology has provided an opportunity to explore new avenues that …
century life. Nanotechnology has provided an opportunity to explore new avenues that …
In search of the Holy Grail: folate-targeted nanoparticles for cancer therapy
Targeted drug therapy or “smart” drug delivery, potentially combined with simultaneous
imaging modalities to monitor the delivery of drugs to specific tissues, is arguably the “holy …
imaging modalities to monitor the delivery of drugs to specific tissues, is arguably the “holy …
Protein corona hampers targeting potential of MUC1 aptamer functionalized SN-38 core–shell nanoparticles
BS Varnamkhasti, H Hosseinzadeh… - International journal of …, 2015 - Elsevier
Nanoparticles have been considered to improve delivery and physicochemical
characteristics of bioactive agents in recent years. In this study, a core–shell chitosan …
characteristics of bioactive agents in recent years. In this study, a core–shell chitosan …