Background A recent meeting of international imaging experts sponsored by the
International Spinal Research Trust (ISRT) and the Wings for Life Foundation identified 5 …

In the past two decades, structural and functional neuroimaging findings have greatly
modified longstanding notions regarding the pathophysiology of amyotrophic lateral …

A first-ever spinal cord imaging meeting was sponsored by the International Spinal
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …

Amyotrophic lateral sclerosis (ALS) exhibits characteristic variability of onset and rate of
disease progression, with inherent clinical heterogeneity making disease quantitation …

Here we present the application of neurite orientation dispersion and density imaging
(NODDI) to the healthy spinal cord in vivo. NODDI provides maps such as the intra-neurite …

Template-based analysis has proven to be an efficient, objective and reproducible way of
extracting relevant information from multi-parametric MRI data. Using common atlases, it is …

Amyotrophic lateral sclerosis (ALS) encompasses a heterogeneous group of phenotypes
with different progression rates, varying degree of extra-motor involvement and divergent …

Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …

Amyotrophic lateral sclerosis (ALS) is associated with considerable clinical heterogeneity
spanning from diverse disability profiles, differences in UMN/LMN involvement, divergent …

The field of spinal cord MRI is lacking a common template, as existing for the brain, which
would allow extraction of multi-parametric data (diffusion-weighted, magnetization transfer …