Detection of SARS-CoV-2 viral proteins and genomic sequences in human brainstem nuclei
Neurological manifestations are common in COVID-19, the disease caused by SARS-CoV-
2. Despite reports of SARS-CoV-2 detection in the brain and cerebrospinal fluid of COVID …
2. Despite reports of SARS-CoV-2 detection in the brain and cerebrospinal fluid of COVID …
Architecture of the subthalamic nucleus
AA Prasad, Å Wallén-Mackenzie - Communications Biology, 2024 - nature.com
The subthalamic nucleus (STN) is a major neuromodulation target for the alleviation of
neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS …
neurological and neuropsychiatric symptoms using deep brain stimulation (DBS). STN-DBS …
Duodenal alpha‐synuclein pathology and enteric gliosis in advanced Parkinson's disease
Background The role of the gut‐brain axis has been recently highlighted as a major
contributor to Parkinson's disease (PD) physiopathology, with numerous studies …
contributor to Parkinson's disease (PD) physiopathology, with numerous studies …
Neurotransmitter and receptor systems in the subthalamic nucleus
Abstract The Subthalamic Nucleus (STh) is a lens-shaped subcortical structure located
ventrally to the thalamus, that despite being embryologically derived from the diencephalon …
ventrally to the thalamus, that despite being embryologically derived from the diencephalon …
Development and in vitro/in vivo comparative characterization of cryopreserved and decellularized tracheal grafts
E Stocco, S Barbon, M Mammana, D Trojan, A Bianchin… - Cells, 2023 - mdpi.com
Tracheal reconstruction represents a challenge when primary anastomosis is not feasible.
Within this scenario, the study aim was to develop a new pig-derived decellularized trachea …
Within this scenario, the study aim was to develop a new pig-derived decellularized trachea …
[HTML][HTML] Beyond the dopaminergic system: lessons learned from levodopa resistant symptoms in Parkinson's disease
Diagnosis and clinical burden in people with Parkinson's disease (PD) is often related to the
cardinal motor features (tremor, bradykinesia, rigidity) and occurs when at least 40–60% of …
cardinal motor features (tremor, bradykinesia, rigidity) and occurs when at least 40–60% of …
ACE2 receptor and TMPRSS2 protein expression patterns in the human brainstem reveal anatomical regions potentially vulnerable to SARS-CoV-2 infection
A Emmi, A Tushevski, A Sinigaglia… - ACS Chemical …, 2023 - ACS Publications
Angiotensin-converting enzyme 2 receptor (ACE2R) is a transmembrane protein expressed
in various tissues throughout the body that plays a key role in the regulation of blood …
in various tissues throughout the body that plays a key role in the regulation of blood …
Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor–Receptor Interactions
Dopamine neurotransmission plays critical roles in regulating complex cognitive and
behavioral processes including reward, motivation, reinforcement learning, and movement …
behavioral processes including reward, motivation, reinforcement learning, and movement …
Carotid body plastic behavior: evidence for D2–H3 receptor–receptor interactions
Dopamine and histamine receptors D2R and H3R are G protein-coupled receptors (GPCRs)
which can establish physical receptor–receptor interactions (RRIs), leading to homo/hetero …
which can establish physical receptor–receptor interactions (RRIs), leading to homo/hetero …
Brainstem anatomy with 7-T MRI: in vivo assessment and ex vivo comparison
G Donatelli, A Emmi, M Costagli, P Cecchi… - European Radiology …, 2023 - Springer
Background The brainstem contains grey matter nuclei and white matter tracts to be
identified in clinical practice. The small size and the low contrast among them make their in …
identified in clinical practice. The small size and the low contrast among them make their in …