As one of the most common complications of diabetes, nephropathy develops in
approximately 40% of diabetic individuals. Although end stage kidney disease is known as …

Abstract Background Na+/K+-ATPase (NKA), an ion pumping enzyme ubiquitously
expressed in various cells, is critically involved in cellular ion homeostasis and signal …

Doxorubicin (DOX) is a potent chemotherapeutic drug for various cancers. Yet, the
cardiotoxic side effects limit its application in clinical uses, in which ferroptosis serves as a …

Protein phosphatases have emerged as critical regulators of phosphoprotein homeostasis in
settings of health and disease. Protein phosphatase 2A (PP2A) encompasses a large …

Na+/K+-ATPase (NKA) plays important roles in maintaining cellular homeostasis.
Conversely, reduced NKA activity has been reported in aging and neurodegenerative …

Abstract Nitroxyl (HNO), one-electron reduced and protonated sibling of nitric oxide (NO), is
a potential regulator of cardiovascular functions. It produces positive inotropic, lusitropic …

Activation of the renin‐angiotensin system (RAS) contributes to the pathogenesis of
cardiovascular diseases. Sodium potassium ATPase (NKA) expression and activity are often …

Dysfunction of the Na+/K+-ATPase (NKA) has been documented in various
neurodegenerative diseases, yet the specific role of NKAα1 in Parkinson's disease (PD) …

Abstract Reduced Na+/K+-ATPase (NKA) activity and NKAα1 expression are engaged in the
pathologies of renal diseases. NKA-mediated Src activation is not the only reason for NKA …

Abstract Reductions in Na+-K+-ATPase (NKA) activity and expression are often observed in
the progress of various reason-induced heart failure (HF). However, NKA α1 mutation or …