Copper metabolism and cuproptosis: molecular mechanisms and therapeutic perspectives in neurodegenerative diseases

X Ban, H Wan, X Wan, Y Tan, X Hu, H Ban… - Current medical …, 2024 - Springer
Copper is an essential trace element, and plays a vital role in numerous physiological
processes within the human body. During normal metabolism, the human body maintains …

Pyroptosis and its role in autoimmune skin disease

Y Yao, Z Wang, J Li, A Peng, Y Cao… - Experimental …, 2024 - Wiley Online Library
Autoimmune skin disease is a kind of heterogeneous disease with complicated
pathogenesis. Many factors such as genetic, infectious, environmental and even …

[HTML][HTML] ALKBH5 facilitates the progression of skin cutaneous melanoma via mediating ABCA1 demethylation and modulating autophagy in an m6A-dependent …

H Wang, S Zhao, H Liu, Y Liu, Z Zhang… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Background: N6-methyladenosine (m 6 A) is the most common and abundant mRNA
modification, playing an essential role in biological processes and tumor development …

[HTML][HTML] Pretreatment can alleviate programmed cell death in mesenchymal stem cells

XX Wan, XM Hu, Q Zhang, K Xiong - World Journal of Stem Cells, 2024 - ncbi.nlm.nih.gov
In this editorial, we delved into the article titled “Cellular preconditioning and mesenchymal
stem cell ferroptosis.” This groundbreaking study underscores a pivotal discovery …

Novel strategies to target cell death signaling in cancer and neurodegenerative diseases: new findings and mechanistic studies

Q Zhang, K Xiong - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Regulated cell death (RCD) is an evolutionarily conserved process that is essential for
organ development and tissue homeostasis maintenance (Hu et al., 2021; Kim et al., 2022; …

Tat-CIRP Peptide Facilitates Frozen Wound Healing by Ameliorating Inflammation and Promoting Angiogenesis

J Li, J Ding, H Wu, C Lu, J Wu, Q Luo - Journal of Inflammation …, 2024 - Taylor & Francis
Background Frostbite is a chemia resulting from cold-induced skin damage. The process of
frostbite is often accompanied by inflammation, and the therapeutic strategies focusing on …

PANoptosis is a Prominent Cell Death Feature in Thoracic Aortic Aneurysm or Dissection

X Xu, Y Zhu, Y Niu, Y Chen, S Fan, D Lu, R Xu… - Experimental Cell …, 2024 - Elsevier
Thoracic aortic aneurysm and dissection (TAAD) is a devastating macrovascular disease,
and its pathogenic mechanisms have not been well clarified. This study aimed to investigate …

Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verification

X Hu, H Shen, R Liu, B Tang, F Deng - Heliyon, 2024 - cell.com
Background Hepatic fibrosis is caused by various liver diseases and eventually develops
into liver cancer. There is no specific drug approved for the treatment of hepatic fibrosis in …

[HTML][HTML] Might Necrotic Keratinocytes Contribute to the Diagnosis and Pathogenesis of Psoriasis?

BÇ Cemil, A Gökçe, GT Aygar… - Dermatology Practical & …, 2024 - ncbi.nlm.nih.gov
Objectives In our study, we aimed to investigate the significance of necrotic keratinocytes in
both the diagnosis and pathogenesis of psoriasis. Methods We analyzed the number of …