The road to reuse of walnut by-products: A comprehensive review of bioactive compounds, extraction and identification methods, biomedical and industrial …

K Zhu, J Ma, J Cong, T Zhang, H Lei, H Xu… - Trends in Food Science …, 2024 - Elsevier
Background Walnuts have high nutrition value and are one of the most popular nuts
worldwide. A large amount of by-products including green walnut husk, walnut shell, walnut …

Phytochemicals and biological activities of walnut septum: A systematic review

L Mateș, ME Rusu, DS Popa - Antioxidants, 2023 - mdpi.com
In the last few decades, scientific evidence has stressed the importance of plants in the
prevention and/or supportive treatment of a plethora of diseases, many of them chronic, age …

Design, synthesis, and SAR studies of novel 4-methoxyphenyl pyrazole and pyrimidine derivatives as potential dual tyrosine kinase inhibitors targeting both EGFR …

AM El-Naggar, AMA Hassan, EB Elkaeed… - Bioorganic …, 2022 - Elsevier
Guided by the pharmacophoric features of both EGFR and VEGFR-2 antagonists, two novel
series of 4-methoxyphenyl pyrazole and pyrimidine derivatives [(4a-c) and (5a-c, 6, 7a-c, 8 …

Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: in vitro, in vivo, molecular docking, molecular dynamics, and …

MM Hammouda, AA Elmaaty, MS Nafie… - Bioorganic …, 2022 - Elsevier
Apparently, tubulin inhibitors binding to the colchicine-binding site (CBS) currently have
outstanding attention for cancer treatment. So, a series of benzo [b] azonin-2-one derivatives …

Anticoagulants as Potential SARS-CoV-2 Mpro Inhibitors for COVID-19 Patients: In Vitro, Molecular Docking, Molecular Dynamics, DFT, and SAR Studies

A Abo Elmaaty, WM Eldehna, M Khattab… - International Journal of …, 2022 - mdpi.com
In this article, 34 anticoagulant drugs were screened in silico against the main protease
(Mpro) of SARS-CoV-2 using molecular docking tools. Idraparinux, fondaparinux …

Design, synthesis, biological evaluation, and SAR studies of novel cyclopentaquinoline derivatives as DNA intercalators, topoisomerase II inhibitors, and apoptotic …

MM Hammoud, AS Nageeb, MA Morsi… - New Journal of …, 2022 - pubs.rsc.org
Herein, a new series of cyclopentaquinoline derivatives (6a–g) were designed and
synthesized based on the pharmacophoric features acquired by some reported DNA …

A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways

MF El-Azab, AA Al-Karmalawy, SA Antar, PA Hanna… - Life sciences, 2022 - Elsevier
Aims The present study aimed to investigate the effect of nano selenium, sildenafil, and their
combination on inflammation, oxidative stress, and apoptosis in streptozotocin-induced …

Winemaking-derived by-products: In-depth characterization and sustainable, advanced pulsed electric field (PEF) processing to a zero-waste-based approach

M Salgado-Ramos, FJ Martí-Quijal… - Journal of …, 2023 - Elsevier
This work aims to establish a novel zero-waste-based assessment for the winemaking-
derived by-products grape stalks (GS), grape marc (GM), and exhausted grape marc (EGM) …

Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS …

M Elagawany, AA Elmaaty, A Mostafa… - Journal of Enzyme …, 2022 - Taylor & Francis
The global outbreak of the COVID-19 pandemic provokes scientists to make a prompt
development of new effective therapeutic interventions for the battle against SARS-CoV-2. A …

Valorisation of hazelnut by-products: current applications and future potential

FD Ceylan, N Adrar, BW Bolling… - Biotechnology and …, 2023 - Taylor & Francis
Hazelnut is one of the most widely consumed nuts around the world. Considering the
nutritional value of hazelnuts, a wide range of hazelnut-based food products are available in …