[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

[HTML][HTML] Acoustic characterization of cavitation intensity: A review

P Wu, X Wang, W Lin, L Bai - Ultrasonics Sonochemistry, 2022 - Elsevier
Cavitation intensity is used to describe the activity of cavitation, and several methods are
developed to identify the intensity of cavitation. This work aimed to provide an overview and …

[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy

KB Bader, E Vlaisavljevich, AD Maxwell - Ultrasound in medicine & biology, 2019 - Elsevier
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

Gauging the likelihood of cavitation from short-pulse, low-duty cycle diagnostic ultrasound

RE Apfel, CK Holland - Ultrasound in medicine & biology, 1991 - Elsevier
Although no deleterious effects from diagnostic ultrasound have been reported in
epidemiologic studies and surveys of widespread clinical usage (Ziskin and Petitti 1988), the …

[HTML][HTML] Therapeutic applications of ultrasound

G Ter Haar - Progress in biophysics and molecular biology, 2007 - Elsevier
Therapeutic applications of ultrasound predate its use in imaging. A range of biological
effects can be induced by ultrasound, depending on the exposure levels used. At low levels …

Acoustic droplet vaporization for therapeutic and diagnostic applications

OD Kripfgans, JB Fowlkes, DL Miller, OP Eldevik… - Ultrasound in medicine …, 2000 - Elsevier
A phase shift droplet emulsion is introduced as an aid to unusual ultrasound (US)
applications. The transpulmonary droplet emulsion (90%< 6 μm diameter) is made by mixing …

Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials

AD Maxwell, CA Cain, TL Hall, JB Fowlkes… - Ultrasound in medicine & …, 2013 - Elsevier
In this study, the negative pressure values at which inertial cavitation consistently occurs in
response to a single, two-cycle, focused ultrasound pulse were measured in several media …

Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously

EC Unger, DW Yellowhair - US Patent 5,558,092, 1996 - Google Patents
2. Background of the Invention Diagnostic ultrasound refers to the imaging of a region of a
human or animal patient using an ultrasound transducer to generate and receive ultrasonic …

Cavitation pressure in water

E Herbert, S Balibar, F Caupin - Physical Review E—Statistical, Nonlinear, and …, 2006 - APS
We investigate the limiting mechanical tension (negative pressure) that liquid water can
sustain before cavitation occurs. The temperature dependence of this quantity is of special …

Effects of ultrasound frequency and tissue stiffness on the histotripsy intrinsic threshold for cavitation

E Vlaisavljevich, KW Lin, A Maxwell, MT Warnez… - Ultrasound in medicine …, 2015 - Elsevier
Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …