During the last decades, lipids have gained much attention due to their involvement in
health and disease. Lipids are required for the formation of membranes and contribute to …

Due to its genetic tractability and increasing wealth of accessible data, the yeast
Saccharomyces cerevisiae is a model system of choice for the study of the genetics …

The inner nuclear membrane (INM) encases the genome and is fused with the outer nuclear
membrane (ONM) to form the nuclear envelope. The ONM is contiguous with the …

The nutrient-and growth factor-responsive kinase mTOR complex 1 (mTORC1) regulates
many processes that control growth, including protein synthesis, autophagy, and …

Acyl lipids in Arabidopsis and all other plants have a myriad of diverse functions. These
include providing the core diffusion barrier of the membranes that separates cells and …

Mitochondria are dynamic organelles whose functional integrity requires a coordinated
supply of proteins and phospholipids. Defined functions of specific phospholipids, like the …

Lipid droplets (LDs) are multi-functional cellular organelles that store energy, and regulate
many aspects of cell physiology. However, our understanding of the biogenesis of LDs …

Triacylglycerol (TAG) is the most important caloric source with respect to energy
homeostasis in animals. In addition to its evolutionarily conserved importance as an energy …

Oils in the form of triacylglycerols are the most abundant energy-dense storage compounds
in eukaryotes, and their metabolism plays a key role in cellular energy balance, lipid …

During the past decade, there has been a paradigm shift in our understanding of the roles of
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …