Machine learning for lung cancer diagnosis, treatment, and prognosis

Y Li, X Wu, P Yang, G Jiang… - Genomics, Proteomics and …, 2022 - academic.oup.com
The recent development of imaging and sequencing technologies enables systematic
advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in …

[HTML][HTML] Informing immunotherapy with multi-omics driven machine learning

Y Li, X Wu, D Fang, Y Luo - npj Digital Medicine, 2024 - nature.com
Progress in sequencing technologies and clinical experiments has revolutionized
immunotherapy on solid and hematologic malignancies. However, the benefits of …

Immortalized bovine satellite cells for cultured meat applications

AJ Stout, MJ Arnett, K Chai, T Guo, L Liao… - ACS synthetic …, 2023 - ACS Publications
For cultured meat to succeed at scale, muscle cells from food-relevant species must be
expanded in vitro in a rapid and reliable manner to produce millions of metric tons of …

[HTML][HTML] Oncogenic viruses as entropic drivers of cancer evolution

I Tempera, PM Lieberman - Frontiers in virology, 2021 - frontiersin.org
Viral infection is an indisputable causal factor for nearly 17% of all human cancers.
However, the diversity and complexity of oncogenic mechanisms raises new questions as to …

Pervasive lesion segregation shapes cancer genome evolution

SJ Aitken, CJ Anderson, F Connor, O Pich… - Nature, 2020 - nature.com
Cancers arise through the acquisition of oncogenic mutations and grow by clonal
expansion,. Here we reveal that most mutagenic DNA lesions are not resolved into a …

[HTML][HTML] Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and …

Z Zhou, J Wang, J Wang, S Yang, R Wang, G Zhang… - Molecular Cancer, 2024 - Springer
Tumor immune microenvironment (TIME) consists of intra-tumor immunological components
and plays a significant role in tumor initiation, progression, metastasis, and response to …

Performance‐weighted‐voting model: An ensemble machine learning method for cancer type classification using whole‐exome sequencing mutation

Y Li, Y Luo - Quantitative biology, 2020 - Wiley Online Library
Background With improvements in next‐generation DNA sequencing technology, lower cost
is needed to collect genetic data. More machine learning techniques can be used to help …

Cancer progression: a single cell perspective

L Ermini, S Taurone, A Greco, M Artico - European Review for …, 2023 - iris.uniroma1.it
Tumor tissues are constituted by a dynamic diversity of malignant and non-malignant cells,
which shape a puzzling biological ecosystem affecting cancer biology and response to …

Imposed mutational meltdown as an antiviral strategy

JD Jensen, RA Stikeleather, TF Kowalik, M Lynch - Evolution, 2020 - academic.oup.com
Following widespread infections of the most recent coronavirus known to infect humans,
SARS-CoV-2, attention has turned to potential therapeutic options. With no drug or vaccine …

[HTML][HTML] Applications of Machine Learning (ML) and Mathematical Modeling (MM) in Healthcare with Special Focus on Cancer Prognosis and Anticancer Therapy …

J Hassan, SM Saeed, L Deka, MJ Uddin, DB Das - Pharmaceutics, 2024 - mdpi.com
The use of data-driven high-throughput analytical techniques, which has given rise to
computational oncology, is undisputed. The widespread use of machine learning (ML) and …