To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M Giustiniano, A Basso, V Mercalli… - Chemical Society …, 2017 - pubs.rsc.org
The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Synthesis and biological activity of vicinal diaryl-substituted 1H-imidazoles

F Bellina, S Cauteruccio, R Rossi - Tetrahedron, 2007 - Elsevier
1. Introduction....................................................................... 4572 2. Synthesis of vicinal diaryl-
substituted 1H-imidazoles..................................... 4572 2.1. Synthesis of 1, 2-diaryl-1H …

Synthesis and anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation activities of some new 2-[(2, 6-dichloroanilino) phenyl] acetic acid derivatives

M Amir, K Shikha - European journal of medicinal chemistry, 2004 - Elsevier
The synthesis of a group of 1, 3, 4-oxadiazoles, 1, 2, 4-triazoles, 1, 3, 4-thiadiazoles and 1, 2,
4-triazine derived from 2-[(2, 6-dichloroanilino) phenyl] acetic acid is described. The …

Design, synthesis and evaluation of antiinflammatory, analgesic and ulcerogenicity studies of novel S-substituted phenacyl-1, 3, 4-oxadiazole-2-thiol and Schiff bases …

SV Bhandari, KG Bothara, MK Raut, AA Patil… - Bioorganic & medicinal …, 2008 - Elsevier
Diclofenac sodium is being used for its anti-inflammatory actions since 28 years, but as all
the NSAIDs are suffering from the deadlier GI toxicities, diclofenac sodium is also not an …

Synthesis and pharmacological evaluation of pyrazoline derivatives as new anti-inflammatory and analgesic agents

M Amir, H Kumar, SA Khan - Bioorganic & medicinal chemistry letters, 2008 - Elsevier
A series of 3-(4-biphenyl)-5-substituted phenyl-2-pyrazolines (2a–h) and 1-benzoyl-3-(4-
biphenyl)-5-substituted phenyl-2-pyrazolines (3a–h) were synthesized by condensation of …

New mononuclear Fe (III), Co (II), Ni (II), Cu (II), and Zn (II) complexes incorporating 4‐{[(2 hydroxyphenyl) imino] methyl} phenyl‐4‐methylbenzenesulfonate (HL) …

NAA Elkanzi, AM Ali, H Hrichi… - Applied Organometallic …, 2022 - Wiley Online Library
Herein, new Fe (III), Co (II), Ni (II), Cu (II), and Zn (II) complexes incorporating 4‐{[(2‐
hydroxyphenyl) imino] methyl} phenyl 4‐methylbenzenesulfonate Schiff‐base ligand (HL) …

Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors

ML de Castro Barbosa, LM Lima, R Tesch… - European journal of …, 2014 - Elsevier
Abstract Novel 2-chloro-4-anilino-quinazolines designed as EGFR and VEGFR-2 dual
inhibitors were synthesized and evaluated for inhibitory effects. EGFR and VEGFR-2 are …

Synthesis and biological evaluation of N-substituted-3, 5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

R Fioravanti, A Bolasco, F Manna, F Rossi… - European journal of …, 2010 - Elsevier
Eighteen new 1-N-substituted-3, 5-diphenyl-2-pyrazoline derivatives have been synthesized
and cyclooxygenase (COX-1 and COX-2) inhibitory activities have been evaluated. The …

Design, Characterization, and DFT exploration of new mononuclear Fe (III) and Co (II) complexes based on Isatin-hydrazone derivative: Anti-inflammatory profiling …

M Albqmi, NAA Elkanzi, AM Ali, A Abdou - Journal of Molecular Structure, 2025 - Elsevier
This research focuses on the synthesis and detailed analysis of novel compounds
encompassing Fe (III)(C1) and Co (II)(C2) ions, featuring 4-(2-oxo-1, 2-dihydro-3H-indol-3 …

Progress in COX-2 inhibitors: a journey so far

AK Chakraborti, SK Garg, R Kumar… - Current medicinal …, 2010 - ingentaconnect.com
The non-steroidal anti-inflammatory drugs (NSAIDs) are diverse group of compounds used
for the treatment of inflammation, since the introduction of acetylsalicylic acid in 1899 …