Fragile X syndrome, the most common heritable form of cognitive impairment, is caused by
epigenetic silencing of the fragile X (FMR1) gene owing to large expansions (> 200 repeats) …

The premutation of the fragile X messenger ribonucleoprotein 1 (FMR1) gene is
characterized by an expansion of the CGG trinucleotide repeats (55 to 200 CGGs) in the …

It has been suggested that neurological problems more frequent in those born preterm are
expressed prior to birth, but owing to technical limitations, this has been difficult to test in …

Since its discovery in 2001, our understanding of fragile X-associated tremor/ataxia
syndrome (FXTAS) has undergone a remarkable transformation. Initially characterized …

Fragile X–associated tremor/ataxia syndrome (FXTAS) is a late‐onset neurodegenerative
disorder that affects some but not all carriers of small, noncoding CGG‐repeat expansions …

Fragile X syndrome (FXS) causes intellectual disability and is the known leading cause of
autism. Common problems in FXS include behavior and social problems. Along with …

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative
disorder affecting approximately 45% of male and 16% of female carriers of the FMR1 …

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative
disorder typically affecting male premutation carriers with 55–200 CGG trinucleotide repeat …

Critical periods are discrete developmental stages when the nervous system is especially
sensitive to stimuli that facilitate circuit maturation. The distinctive landscapes assumed by …

Background Fragile X–associated tremor/ataxia syndrome is a neurodegenerative disease
of late onset developed by carriers of the premutation in the fragile x mental retardation 1 …