Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

[HTML][HTML] Western diet and the immune system: an inflammatory connection

A Christ, M Lauterbach, E Latz - Immunity, 2019 - cell.com
The consumption of Western-type calorically rich diets combined with chronic overnutrition
and a sedentary lifestyle in Western societies evokes a state of chronic metabolic …

[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

The incretin hormone GLP‐1 and mechanisms underlying its secretion: 肠促胰岛素激素GLP‐1 及其潜在的分泌机制

L Tian, T Jin - Journal of diabetes, 2016 - Wiley Online Library
摘要胰高血糖素样肽‐1 (Glucagon‐like peptide‐1, GLP‐1) 是一种细胞类型特异性的胰高血糖
素原翻译后产物. 它是由胰高血糖素原基因所编码的, 在激素, 神经元以及营养的刺激下主要由肠 …

Treatment of type 2 diabetes: challenges, hopes, and anticipated successes

MA Nauck, J Wefers, JJ Meier - The lancet Diabetes & endocrinology, 2021 - thelancet.com
Despite the successful development of new therapies for the treatment of type 2 diabetes,
such as glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose …

Internal senses of the vagus nerve

SL Prescott, SD Liberles - Neuron, 2022 - cell.com
The vagus nerve is an indispensable body-brain connection that controls vital aspects of
autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes …

Gut–brain circuits for fat preference

M Li, HE Tan, Z Lu, KS Tsang, AJ Chung, CS Zuker - Nature, 2022 - nature.com
The perception of fat evokes strong appetitive and consummatory responses. Here we show
that fat stimuli can induce behavioural attraction even in the absence of a functional taste …

Monounsaturated fatty acids in obesity-related inflammation

G Ravaut, A Légiot, KF Bergeron… - International journal of …, 2020 - mdpi.com
Obesity is an important aspect of the metabolic syndrome and is often associated with
chronic inflammation. In this context, inflammation of organs participating in energy …