Hemoglobinopathies are hereditary disorders of the hemoglobin molecule with a high
prevalence worldwide. Brazil has a prevalence of 0.1 to 0.3% of newborns with sickle cell …

In order to determine the contribution of alpha-thalassemia to microcytosis and
hypochromia, 339 adult outpatients seen at Unicamp University Hospital (with the exception …

Abstract Background and Aim: The present study aimed to evaluate the incidence and
etiology of chronic liver abnormalities in 70 living patients with sickle cell disease from the …

The aim of the present work was to examine possible genetic risk factors related to the
occurrence of cerebrovascular disease (CVD) in Brazilian population, the frequency of βS …

Alpha-thalassemia is the most common inherited disorder of hemoglobin synthesis.
Genomic deletions involving the alpha-globin gene cluster on chromosome 16p13. 3 are the …

Alpha-thalassemias are among the most common genetic diseases in the world. They are
characterized by hypochromic and microcytic anemia and great clinical variability, ranging …

Alpha thalassemia is the most frequently inherited disease in the world, including the
Brazilian population, affecting mainly Asian descendents and some African groups. Data …

In October 2005, our laboratory performed routine testing of a 23-year-old female refugee
from Sudan. The full blood examination demonstrated microcytosis and hypochromia …

The aim of this study was to determine the frequency of beta S-globin gene (βS globin)
haplotypes and alpha thalassemia with 3.7 kb deletion (− α3. 7kb thalassemia) in the …

OBJECTIVE: Sickle cell anemia and the interaction S/Beta thalassemia differ in
hematological values due to microcytosis and hypochromia caused by the thalassemic …