Evaluation of sepsis prediction models before onset of treatment

F Kamran, D Tjandra, A Heiler, J Virzi, K Singh, JE King… - NEJM AI, 2024 - ai.nejm.org
Background Timely interventions, such as antibiotics and intravenous fluids, have been
associated with reduced mortality in patients with sepsis. Artificial intelligence (AI) models …

Evidence Underpinning the Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock Management Bundle (SEP-1) A Systematic Review

DJ Pepper, D Jaswal, J Sun, J Welsh… - Annals of internal …, 2018 - acpjournals.org
This article has been corrected. To see what has changed, please read the Letter to the
Editor and the authors' response. The original version (PDF) is appended to this article as a …

[HTML][HTML] Driving blind: instituting SEP-1 without high quality outcomes data

J Wang, JR Strich, WN Applefeld, J Sun… - Journal of thoracic …, 2020 - ncbi.nlm.nih.gov
Abstract In 2015, the Centers for Medicare and Medicaid Services (CMS) instituted an all-or-
none sepsis performance measure bundle (SEP-1) to promote high-quality, cost-effective …

Compliance with the national SEP-1 quality measure and association with sepsis outcomes: a multicenter retrospective cohort study

C Rhee, MR Filbin, AF Massaro, AL Bulger… - Critical care …, 2018 - journals.lww.com
Objectives: Many septic patients receive care that fails the Centers for Medicare and
Medicaid Services' SEP-1 measure, but it is unclear whether this reflects meaningful lapses …

Epidemiology of hospital-onset versus community-onset sepsis in US hospitals and association with mortality: a retrospective analysis using electronic clinical data

C Rhee, R Wang, Z Zhang, D Fram, SS Kadri… - Critical care …, 2019 - journals.lww.com
Objectives: Prior studies have reported that hospital-onset sepsis is associated with higher
mortality rates than community-onset sepsis. Most studies, however, have used inconsistent …

The 2018 surviving sepsis campaign's treatment bundle: when guidelines outpace the evidence supporting their use

R Spiegel, JD Farkas, P Rola, JE Kenny… - Annals of …, 2019 - annemergmed.com
Inadvertent catastrophes often arise from good intentions. One recent medical care example
of this phenomenon was the 2002 Centers for Medicare & Medicaid Services (CMS) …

POINT: should the Surviving Sepsis Campaign guidelines be retired? Yes

PE Marik, JD Farkas, R Spiegel, S Weingart, S Aberegg… - Chest, 2019 - journal.chestnet.org
Concern regarding the Surviving Sepsis Campaign (SSC) guidelines dates to their
inception. Guideline development was sponsored by Eli Lilly and Edwards Life Sciences as …

Early care of adults with suspected sepsis in the emergency department and out-of-hospital environment: a consensus-based task force report

DM Yealy, NM Mohr, NI Shapiro, A Venkatesh… - Annals of emergency …, 2021 - Elsevier
Sepsis is a major cause of hospital death in the United States (US) 1 and is associated with
over 850,000 annual emergency department visits. 2 Despite advances in care, patients with …

Does early follow-up improve the outcomes of sepsis survivors discharged to home health care?

P Deb, CM Murtaugh, KH Bowles, ME Mikkelsen… - Medical care, 2019 - journals.lww.com
Background: There is little evidence to guide the care of over a million sepsis survivors
following hospital discharge despite high rates of hospital readmission. Objective: We …

Implications of centers for medicare & medicaid services severe sepsis and septic shock early management bundle and initial lactate measurement on the …

X Han, DP Edelson, A Snyder, N Pettit, S Sokol, C Barc… - Chest, 2018 - Elsevier
Background Sepsis remains a significant cause of morbidity and mortality in the United
States, leading to the implementation of the Severe Sepsis and Septic Shock Early …