FOXM1 is a transcription factor required for a wide spectrum of essential biological functions,
including DNA damage repair, cell proliferation, cell cycle progression, cell renewal, cell …

Oncogenic transcription factor FOXM1 is overexpressed in the majority of human cancers. In
addition, FOXM1 has been implicated in cell migration, invasion, angiogenesis and …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …

Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …

The centrosomal protein, CEP 55, is a key regulator of cytokinesis, and its overexpression is
linked to genomic instability, a hallmark of cancer. However, the mechanism by which it …

Efficient double-strand break repair in eukaryotes requires manipulation of chromatin
structure. ATP-dependent chromatin remodelling enzymes facilitate different DNA repair …

Increased ubiquitin-specific protease 5 (USP5) has been associated with tumorigenesis of
malignancy including glioblastoma, melanoma and hepatocellular carcinoma. However, the …

FOXO3a and FOXM1 are two forkhead transcription factors with antagonistic roles in cancer
and DNA damage response. FOXO3a functions like a typical tumour suppressor, whereas …

Circular RNAs (circRNAs) are a large class of endogenous non-coding RNAs that function
as regulators in various cells and tissues. Here, the function and mechanism of …

This research article describes an approach to modify the thiazolidinedione scaffold to
produce test drugs capable of binding to, and inhibit, the in vitro transcriptional activity of the …