Shaping bacterial gene expression by physiological and proteome allocation constraints
M Scott, T Hwa - Nature Reviews Microbiology, 2023 - nature.com
Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …
regulation, with the machinery of protein synthesis tacitly relegated to the background …
Metabolomics and Microbial Metabolism: Toward a Systematic Understanding
D Holbrook-Smith, J Trouillon… - Annual Review of …, 2023 - annualreviews.org
Over the past decades, our understanding of microbial metabolism has increased
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …
The architecture of metabolic networks constrains the evolution of microbial resource hierarchies
Microbial strategies for resource use are an essential determinant of their fitness in complex
habitats. When facing environments with multiple nutrients, microbes often use them …
habitats. When facing environments with multiple nutrients, microbes often use them …
Synthetic robust perfect adaptation achieved by negative feedback coupling with linear weak positive feedback
Z Sun, W Wei, M Zhang, W Shi, Y Zong… - Nucleic Acids …, 2022 - academic.oup.com
Unlike their natural counterparts, synthetic genetic circuits are usually fragile in the face of
environmental perturbations and genetic mutations. Several theoretical robust genetic …
environmental perturbations and genetic mutations. Several theoretical robust genetic …
[HTML][HTML] Regulation of hierarchical carbon substrate utilization, nitrogen fixation, and root colonization by the Hfq/Crc/CrcZY genes in Pseudomonas stutzeri
F Lv, Y Zhan, W Lu, X Ke, Y Shao, Y Ma, J Zheng… - Iscience, 2022 - cell.com
Bacteria of the genus Pseudomonas consume preferred carbon substrates in nearly reverse
order to that of enterobacteria, and this process is controlled by RNA-binding translational …
order to that of enterobacteria, and this process is controlled by RNA-binding translational …
[HTML][HTML] The importance of understanding the regulation of bacterial metabolism
Many bacterial species have biotechnological applications, for example in the production of
compounds of interest by fermentation or biotransformation, the handling of waste and the …
compounds of interest by fermentation or biotransformation, the handling of waste and the …
Starvation responses impact interaction dynamics of human gut bacteria Bacteroides thetaiotaomicron and Roseburia intestinalis
Bacterial growth often alters the environment, which in turn can impact interspecies
interactions among bacteria. Here, we used an in vitro batch system containing mucin beads …
interactions among bacteria. Here, we used an in vitro batch system containing mucin beads …
Making sense of gene expression control by flux sensing
Cells regulate metabolic fluxes by changing enzyme levels according to their needs, but
how do they regulate something that cannot be measured directly? In this issue of Nature …
how do they regulate something that cannot be measured directly? In this issue of Nature …
Modeling interactions of Clostridium cadaveris and Clostridium sporogenes in anaerobic acidogenesis of glucose and peptone
MAH Jannat, SH Park, S Hwang - Bioresource Technology, 2024 - Elsevier
This study focuses on developing a mathematical model to assess interaction among
acidogenic bacteria during the anaerobic degradation of two substrates. Clostridium …
acidogenic bacteria during the anaerobic degradation of two substrates. Clostridium …
CRISPR/dCas12a knock-down of Acidithiobacillus ferrooxidans electron transport chain bc1 complexes enables enhanced metal sulfide bioleaching
Acidithiobacillus ferrooxidans is an acidophilic chemolithoautotroph that plays an important
role in biogeochemical iron and sulfur cycling and is a member of the consortia used in …
role in biogeochemical iron and sulfur cycling and is a member of the consortia used in …