Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

Instrumentation for hydrogenative parahydrogen-based hyperpolarization techniques

AB Schmidt, CR Bowers, K Buckenmaier… - Analytical …, 2022 - ACS Publications
The unique properties of the entangled, antisymmetric nuclear spin state of dihydrogen,
parahydrogen (pH2), has intrigued physicists, chemists, and other scientists for almost a …

Preparation of biogenic gas vesicle nanostructures for use as contrast agents for ultrasound and MRI

A Lakshmanan, GJ Lu, A Farhadi, SP Nety, M Kunth… - Nature protocols, 2017 - nature.com
Gas vesicles (GVs) are a unique class of gas-filled protein nanostructures that are
detectable at subnanomolar concentrations and whose physical properties allow them to …

Facile hyperpolarization chemistry for molecular imaging and metabolic tracking of [1–13C] pyruvate in vivo

K MacCulloch, A Browning, DOG Bedoya… - Journal of magnetic …, 2023 - Elsevier
Hyperpolarization chemistry based on reversible exchange of parahydrogen, also known as
Signal Amplification By Reversible Exchange (SABRE), is a particularly simple approach to …

Generalizing, extending, and maximizing nitrogen-15 hyperpolarization induced by parahydrogen in reversible exchange

JFP Colell, AWJ Logan, Z Zhou… - The Journal of …, 2017 - ACS Publications
Signal Amplification by Reversible Exchange (SABRE) is a fast and convenient NMR
hyperpolarization method that uses cheap and readily available para-hydrogen as a …

Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts

S Jannin, JN Dumez, P Giraudeau… - Journal of Magnetic …, 2019 - Elsevier
Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear
magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of …

Hyper-CEST NMR of metal organic polyhedral cages reveals hidden diastereomers with diverse guest exchange kinetics

J Jayapaul, S Komulainen, VV Zhivonitko… - Nature …, 2022 - nature.com
Guest capture and release are important properties of self-assembling nanostructures. Over
time, a significant fraction of guests might engage in short-lived states with different …

MATRESHCA: Microtesla Apparatus for Transfer of Resonance Enhancement of Spin Hyperpolarization via Chemical Exchange and Addition

S Nantogma, MRH Chowdhury, MSH Kabir… - Analytical …, 2024 - ACS Publications
We present an integrated, open-source device for parahydrogen-based hyperpolarization
processes in the microtesla field regime with a cost of components of less than $7000. The …

Heterogeneous Catalysis and Parahydrogen‐Induced Polarization

EV Pokochueva, DB Burueva, OG Salnikov… - …, 2021 - Wiley Online Library
Parahydrogen‐induced polarization with heterogeneous catalysts (HET‐PHIP) has been a
subject of extensive research in the last decade since its first observation in 2007. While …