Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

[HTML][HTML] Adipose tissue and insulin resistance in obese

B Ahmed, R Sultana, MW Greene - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019 - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Injectable hydrogels for cardiac tissue engineering

B Peña, M Laughter, S Jett, TJ Rowland… - Macromolecular …, 2018 - Wiley Online Library
In light of the limited efficacy of current treatments for cardiac regeneration, tissue
engineering approaches have been explored for their potential to provide mechanical …

Thermogels: In situ gelling biomaterial

SS Liow, Q Dou, D Kai, AA Karim, K Zhang… - ACS Biomaterials …, 2016 - ACS Publications
In situ gel delivery systems are preferred over conventional systems due to sustained and
prolonged release action of therapeutic payload onto the targeted site. Thermogel, a form of …

Biomaterials for personalized cell therapy

AL Facklam, LR Volpatti, DG Anderson - Advanced materials, 2020 - Wiley Online Library
Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

Design of injectable materials to improve stem cell transplantation

LM Marquardt, SC Heilshorn - Current stem cell reports, 2016 - Springer
Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Hydrogel based approaches for cardiac tissue engineering

L Saludas, S Pascual-Gil, F Prósper, E Garbayo… - International journal of …, 2017 - Elsevier
Heart failure still represents the leading cause of death worldwide. Novel strategies using
stem cells and growth factors have been investigated for effective cardiac tissue …

Antifibrotic therapies to control cardiac fibrosis

Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …

Injectable supramolecular polymer–nanoparticle hydrogels enhance human mesenchymal stem cell delivery

AK Grosskopf, GA Roth, AAA Smith… - Bioengineering & …, 2020 - Wiley Online Library
Stem cell therapies have emerged as promising treatments for injuries and diseases in
regenerative medicine. Yet, delivering stem cells therapeutically can be complicated by …