Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders
characterized by activated Janus kinase (JAK)–signal transducer and activator of …

Myeloproliferative neoplasms (MPNs) are the leading causes of unusual site thrombosis,
affecting nearly 40% of individuals with conditions like Budd–Chiari syndrome or portal vein …

The developmental history of blood cancer begins with mutation acquisition and the
resulting malignant clone expansion. The two most prevalent driver mutations found in …

Transformation from chronic (CP) to blast phase (BP) in myeloproliferative neoplasm (MPN)
remains poorly characterized, and no specific mutation pattern has been highlighted. BP …

Myeloproliferative neoplasms are stem cell–driven cancers associated with a large burden
of morbidity and mortality. Most patients present with early-stage disease, but a substantial …

Here, we reviewed clinical-morphological data and investigated mutational profiles by NGS
in a single-center series of 58 consecutive MPN-SVT patients admitted to our hospital …

Acute leukemias, mainly consisting of acute lymphoblastic leukemia (ALL) and acute
myeloid leukemia (AML), comprise a major diagnostic group among hematologic cancers …

Myeloproliferative neoplasms are characterized by the acquisition at the hematopoietic stem
cell level of driver mutations targeting the JAK/STAT pathway. In addition, they also often …

Clonal hematopoiesis (CH) occurs in hematopoietic stem cells with increased risks of
progressing to hematologic malignancies. CH mutations are predominantly found in aged …

Primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET)
form the classical BCR-ABL1-negative myeloproliferative neoplasms (MPNs) that are driven …