Chromone: a valid scaffold in medicinal chemistry
Chromones are a group of naturally occurring compounds that are ubiquitous in nature,
especially in plants. The word chromone is derived from the Greek word chroma, meaning …
especially in plants. The word chromone is derived from the Greek word chroma, meaning …
[HTML][HTML] Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression
T Nakanishi, DD Ross - Chinese journal of cancer, 2012 - ncbi.nlm.nih.gov
Breast cancer resistance protein (BCRP)/ATP-binding cassette subfamily G member 2
(ABCG2) is an ATP-binding cassette (ABC) transporter identified as a molecular cause of …
(ABCG2) is an ATP-binding cassette (ABC) transporter identified as a molecular cause of …
[HTML][HTML] Human ABCG2: structure, function, and its role in multidrug resistance
W Mo, JT Zhang - … journal of biochemistry and molecular biology, 2012 - ncbi.nlm.nih.gov
Human ABCG2 is a member of the ATP-binding cassette (ABC) transporter superfamily and
is known to contribute to multidrug resistance (MDR) in cancer chemotherapy. Among ABC …
is known to contribute to multidrug resistance (MDR) in cancer chemotherapy. Among ABC …
A review on anticancer potentials of benzothiazole derivatives
Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
Development of inhibitors of ATP-binding cassette drug transporters–present status and challenges
S Shukla, CP Wu, SV Ambudkar - Expert opinion on drug …, 2008 - Taylor & Francis
Background: Multi-drug resistance (MDR) of cancer cells is an obstacle to effective
chemotherapy of cancer. The ATP-binding cassette (ABC) transporters, including P …
chemotherapy of cancer. The ATP-binding cassette (ABC) transporters, including P …
ABCG2: structure, function and role in drug response
O Polgar, RW Robey, SE Bates - Expert opinion on drug …, 2008 - Taylor & Francis
ABCG2 was discovered in multi-drug-resistant cancer cells, with the identification of
chemotherapeutic agents, such as mitoxantrone, flavopiridol, methotrexate and irinotecan as …
chemotherapeutic agents, such as mitoxantrone, flavopiridol, methotrexate and irinotecan as …
An update on natural occurrence and biological activity of chromones
The chemistry of chromones is very well known. This system is widely used in organic
chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the …
chemistry as an intermediate compound for the synthesis of numerous hetrocycles. On the …
Synthesis, structure–activity relationship of novel substituted 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates as potential anti-mycobacterial and anticancer …
Abstract Series of 4H-chromen-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives 7a–
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
7zb, 8a–8d and 9a–9d were synthesized and screened for their in vitro anti-mycobacterial …
[HTML][HTML] Estrogen receptor ligands: a review (2013–2015)
S Farzaneh, A Zarghi - Scientia pharmaceutica, 2016 - mdpi.com
Estrogen receptors (ERs) are a group of compounds named for their importance in both
menstrual and estrous reproductive cycles. They are involved in the regulation of various …
menstrual and estrous reproductive cycles. They are involved in the regulation of various …
[HTML][HTML] Synthesis and antimicrobial activity of chromone-linked 2-pyridone fused with 1, 2, 4-triazoles, 1, 2, 4-triazines and 1, 2, 4-triazepines ring systems
TES Ali, MA Ibrahim - Journal of the Brazilian Chemical Society, 2010 - SciELO Brasil
Three series of novel fused nitrogen heterocyclic systems such as 1, 2, 4-triazolo [1, 5-α]
pyridines (5-7 and 9), pyrido [1, 2-b][1, 2, 4] triazines (10, 11, 13 and 15), and pyrido [1, 2 …
pyridines (5-7 and 9), pyrido [1, 2-b][1, 2, 4] triazines (10, 11, 13 and 15), and pyrido [1, 2 …