The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Q Hu, Y Xiong, GH Zhu, YN Zhang, YW Zhang… - MedComm, 2022 - Wiley Online Library
The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

An updated review of computer‐aided drug design and its application to COVID‐19

AB Gurung, MA Ali, J Lee, MA Farah… - BioMed research …, 2021 - Wiley Online Library
The recent outbreak of the deadly coronavirus disease 19 (COVID‐19) pandemic poses
serious health concerns around the world. The lack of approved drugs or vaccines continues …

[HTML][HTML] Repurposing of phytomedicine-derived bioactive compounds with promising anti-SARS-CoV-2 potential: Molecular docking, MD simulation and drug-likeness …

M Rudrapal, N Gogoi, D Chetia, J Khan… - Saudi journal of …, 2022 - Elsevier
In view of the potential of traditional plant-based remedies (or phytomedicines) in the
management of COVID-19, the present investigation was aimed at finding novel anti-SARS …

Less COVID-19 deaths in southern and insular Italy explained by forest bathing, Mediterranean environment, and antiviral plant volatile organic compounds

V Roviello, GN Roviello - Environmental chemistry letters, 2021 - Springer
Abstract The coronavirus disease 2019 (COVID-19) is causing major sanitary and
socioeconomic issues, yet some locations are less impacted than others. While densely …

Pseudoscience and fraudulent products for COVID-19 management

VP Chavda, SS Sonak, NK Munshi… - … Science and Pollution …, 2022 - Springer
As of now, the COVID-19 pandemic has become uncontrolled and is spreading widely
throughout the world. Additionally, new variants of the mutated viral variants have been …

[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

M Rudrapal, I Celik, S Chinnam, MA Ansari… - Saudi Journal of …, 2022 - Elsevier
The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …

[HTML][HTML] Herbal concoction unveiled: a computational analysis of phytochemicals' pharmacokinetic and toxicological profiles using novel approach methodologies …

M Rai, AV Singh, N Paudel, A Kanase, E Falletta… - Current Research in …, 2023 - Elsevier
Herbal medications have an extensive history of use in treating various diseases, attributed
to their perceived efficacy and safety. Traditional medicine practitioners and contemporary …

An exhaustive comprehension of the role of herbal medicines in Pre-and Post-COVID manifestations

SK Prajapati, A Malaiya, G Mishra, D Jain… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance The coronavirus disease (COVID-19) has relentlessly
spread all over the world even after the advent of vaccines. It demands management …

Pulmonary drug delivery: an effective and convenient delivery route to combat COVID-19

S Alipour, L Mahmoudi, F Ahmadi - Drug delivery and translational …, 2023 - Springer
The recent outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China has spread
rapidly around the world, leading to a widespread and urgent effort to develop and use …

[HTML][HTML] The emerging role of miRNAs in the pathogenesis of COVID-19: Protective effects of nutraceutical polyphenolic compounds against SARS-CoV-2 infection

CY Yang, YH Chen, PJ Liu, WC Hu… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can cause
immunosuppression and cytokine storm, leading to lung damage and death. The clinical …