Reactive oxygen species (ROS) mediate lipid peroxidation and produce 4-hydroxynonenal
and other related products, which play an important role in the process of cell death …

Free radicals and oxidants are involved in physiological signaling pathways, although an
imbalance between pro-oxidant and anti-oxidant systems in favor of the former leads to …

Lipid peroxidation can be described generally as a process under which oxidants such as
free radicals attack lipids containing carbon‐carbon double bond (s), especially …

Radiotherapy is one of the major cancer treatment strategies. Exposure to penetrating
radiation causes cellular stress, directly or indirectly, due to the generation of reactive …

Over the last decade, a growing interest in the improvement of radiation therapies has led to
the development of gold-based nanomaterials as radiosensitizer. Although the …

The products of lipid peroxidation, resulting from cell metabolism as well as the action of
external physical factors and xenobiotics, have a significant impact on cell functions. One of …

Polyunsaturated fatty acids are susceptible to peroxidation and they yield various
degradation products, including the main α, β-unsaturated hydroxyalkenal, 4-hydroxy-2, 3 …

Ferroptosis, a genetically and biochemically distinct form of programmed cell death, is
characterised by an iron-dependent accumulation of lipid peroxides. Therapy-resistant …

Under physiological conditions, cells are in a stable state known as redox homeostasis,
which is maintained by the balance between continuous ROS/RNS generation and several …

Immunotherapy has revolutionized cancer treatment, dramatically improving survival rates of
melanoma and lung cancer patients. Nevertheless, immunotherapy is almost ineffective …