Additive manufacturing in drug delivery: Innovative drug product design and opportunities for industrial application
H Ragelle, S Rahimian, EA Guzzi… - Advanced Drug Delivery …, 2021 - Elsevier
Additive manufacturing (AM) or 3D printing is enabling new directions in product design. The
adoption of AM in various industrial sectors has led to major transformations. Similarly, AM …
adoption of AM in various industrial sectors has led to major transformations. Similarly, AM …
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence… - Annual review of …, 2018 - annualreviews.org
The pharmaceutical industry has found new applications for the use of continuous
processing for the manufacture of new therapies currently in development. The …
processing for the manufacture of new therapies currently in development. The …
Integrated continuous pharmaceutical technologies—a review
Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …
and development of new active compounds; meanwhile, the structure of the production …
Recent progress in continuous manufacturing of oral solid dosage forms
V Vanhoorne, C Vervaet - International Journal of Pharmaceutics, 2020 - Elsevier
Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …
industry. Although the benefits related to the quality and cost of continuous manufacturing …
A critical review of recent trends, and a future perspective of optical spectroscopy as PAT in biopharmaceutical downstream processing
As competition in the biopharmaceutical market gets keener due to the market entry of
biosimilars, process analytical technologies (PATs) play an important role for process …
biosimilars, process analytical technologies (PATs) play an important role for process …
Review of real-time release testing of pharmaceutical tablets: State-of-the art, challenges and future perspective
D Markl, M Warman, M Dumarey, EL Bergman… - International journal of …, 2020 - Elsevier
In the last decade significant advances have been made in process analytical technologies
and digital manufacturing of pharmaceutical oral solid dosage forms leading to enhanced …
and digital manufacturing of pharmaceutical oral solid dosage forms leading to enhanced …
A review of current techniques for the evaluation of powder mixing
M Asachi, E Nourafkan, A Hassanpour - Advanced Powder Technology, 2018 - Elsevier
Blending a mixture of powders to a homogeneous system is a crucial step in many
manufacturing processes. To achieve a high quality of the end product, powder mixtures …
manufacturing processes. To achieve a high quality of the end product, powder mixtures …
Detailed modeling and process design of an advanced continuous powder mixer
A vertical in-line continuous powder mixing device (CMT–Continuous Mixing Technology)
has been modelled with the discrete element method (DEM) utilizing a calibrated cohesive …
has been modelled with the discrete element method (DEM) utilizing a calibrated cohesive …
PAT implementation for advanced process control in solid dosage manufacturing–A practical guide
S Sacher, J Poms, J Rehrl, JG Khinast - International Journal of …, 2022 - Elsevier
The implementation of continuous pharmaceutical manufacturing requires advanced control
strategies rather than traditional end product testing or an operation within a small range of …
strategies rather than traditional end product testing or an operation within a small range of …
Hot-melt extrusion: from theory to application in pharmaceutical formulation—where are we now?
Hot-melt extrusion (HME) is a globally recognized, robust, effective technology that
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …
enhances the bioavailability of poorly soluble active pharmaceutical ingredients and offers …