Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10
million serious allergies and more than a million deaths each year. Global mortality owing to …

Fungi are ubiquitous. Yet, despite our frequent exposure to commensal fungi of the normal
mammalian microbiota and environmental fungi, serious, systemic fungal infections are rare …

Infections with Candida spp. have different manifestations in humans, ranging from mucosal
to bloodstream and deep-seated disseminated infections. Immunocompromised patients …

Background Association studies of various gene variants in neonatal sepsis show conflicting
results. Objective We performed a systematic review of candidate gene association studies …

The immune system starts to develop early in embryogenesis. However, at birth it is still
immature and associated with high susceptibility to infection. Adaptation to extrauterine …

Infections are a major cause of childhood mortality. We investigated components of the lectin
pathway of complement activation in the context of sepsis at both genetic and protein levels …

This paper summarizes the data concerning soluble defense lectins (mannan‐binding lectin,
M‐ficolin, L‐ficolin, and H‐ficolin) with the unique ability to activate complement and their …

Sepsis is a major cause of neonatal morbidity and mortality, especially in vulnerable preterm
populations. Immature immune defenses, and environmental and maternal factors contribute …

Background The imbalance between pro‐inflammatory and anti‐inflammatory cytokines may
play a role in the development of bronchopulmonary dysplasia (BPD) in preterm infants …

Several studies have evaluated the association between mannose-binding lectin (MBL)
polymorphisms and sepsis. However, the results are inconclusive and conflicting. To better …