Humans are unable to synthesise l‐ascorbic acid (L‐AA, ascorbate, vitamin C), and are thus
entirely dependent upon dietary sources to meet needs. In both plant and animal …

Ascorbic acid (vitamin C) is an abundant component of plants. It reaches a concentration of
over 20 m M in chloroplasts and occurs in all cell compartments, including the cell wall. It …

All aerobically growing organisms suffer exposure to oxidative stress, caused by partially
reduced forms of molecular oxygen, known as reactive oxygen species (ROS). These are …

The past few years have provided many advances in the role and biosynthesis of l‐ascorbic
acid (AsA) in plants. There is an increasing body of evidence confirming that AsA plays an …

▪ Abstract The structure of the familiar antioxidant l-ascorbic acid (vitamin C) was described
in 1933 yet remarkably, its biosynthesis in plants remained elusive until only recently. It …

Ascorbic acid (vitamin C) is an enzyme co-factor in eukaryotes that also plays a critical role
in protecting photosynthetic eukaryotes against damaging reactive oxygen species derived …

Despite the plethora of reviews on l-ascorbic acid, few stray beyond its established roles as
an agent in redox-associated reactions or its biomedical importance. Here, an attempt is …

It is widely accepted that the predominant ascorbate biosynthesis pathway in green plants is
via GDP-mannose and l-galactose. d-galacturonic, d-glucuronic acid and GDP-l-gulose …

Many enzymes use one or more cofactors, such as biotin, heme, or flavin. These cofactors
may be bound to the enzyme in a noncovalent or covalent manner. Although most …

Biosynthesis of l-ascorbate (vitamin C) occurs by different pathways in plants and mammals.
Yeast contain d-erythroascorbate, a C 5 analog of ascorbate. UDP-d-glucuronic acid is the …