PARP inhibitors: clinical relevance, mechanisms of action and tumor resistance
The Poly (ADP-ribose) polymerase (PARP) family has many essential functions in cellular
processes, including the regulation of transcription, apoptosis and the DNA damage …
processes, including the regulation of transcription, apoptosis and the DNA damage …
Lung cancer in China: current and prospect
F Wu, L Wang, C Zhou - Current opinion in oncology, 2021 - journals.lww.com
Lung cancer in China: current and prospect : Current Opinion in Oncology Lung cancer in
China: current and prospect : Current Opinion in Oncology Log in or Register Subscribe to …
China: current and prospect : Current Opinion in Oncology Log in or Register Subscribe to …
Changing profiles of cancer burden worldwide and in China: a secondary analysis of the global cancer statistics 2020
Background: Cancer is one of the leading causes of death globally, but its burden is not
uniform. GLOBOCAN 2020 has newly updated the estimates of cancer burden. This study …
uniform. GLOBOCAN 2020 has newly updated the estimates of cancer burden. This study …
Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type …
JS Lou, LP Zhao, ZH Huang, XY Chen, JT Xu, WCS Tai… - Phytomedicine, 2021 - Elsevier
Background Cisplatin (DDP) is the first-in-class drug for advanced and non-targetable non-
small-cell lung cancer (NSCLC). A recent study indicated that DDP could slightly induce non …
small-cell lung cancer (NSCLC). A recent study indicated that DDP could slightly induce non …
NRF2, a Superstar of Ferroptosis
R Yan, B Lin, W Jin, L Tang, S Hu, R Cai - Antioxidants, 2023 - mdpi.com
Ferroptosis is an iron-dependent and lipid peroxidation-driven cell death cascade, occurring
when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2 …
when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2 …
COVID-19 pandemic in China: Context, experience and lessons
W Xu, J Wu, L Cao - Health policy and technology, 2020 - Elsevier
The first cluster of COVID-19 cases was reported in Wuhan, China on December 29th, 2019.
Since then, China has experienced a pandemic of COVID-19. Objective: This study aims to …
Since then, China has experienced a pandemic of COVID-19. Objective: This study aims to …
Antigen-down PEC immunosensor for CYFRA21-1 detection based on photocurrent polarity switching strategy
J Zhang, X Xue, Y Du, J Zhao, H Ma, X Ren… - Analytical …, 2022 - ACS Publications
In this work, an antigen-down photoelectrochemical (PEC) immunosensor based on a signal
polarity switching strategy for the detection of cytokeratin 19 fragment 21-1 (CYFRA21-1) …
polarity switching strategy for the detection of cytokeratin 19 fragment 21-1 (CYFRA21-1) …
[HTML][HTML] Tobacco and the lung cancer epidemic in China
M Parascandola, L Xiao - Translational lung cancer research, 2019 - ncbi.nlm.nih.gov
China is in the midst of a lung cancer epidemic on an unprecedented scale. In 2015, there
were an estimated 733,000 new lung cancer cases (17% of total cancer incidence) and …
were an estimated 733,000 new lung cancer cases (17% of total cancer incidence) and …
Self‐assembled peptide‐based nanodrugs: molecular design, synthesis, functionalization, and targeted tumor bioimaging and biotherapy
Functional nanomaterials as nanodrugs based on the self‐assembly of inorganics,
polymers, and biomolecules have showed wide applications in biomedicine and tissue …
polymers, and biomolecules have showed wide applications in biomedicine and tissue …
Impact of cancer diagnoses on the outcomes of patients with COVID-19: a systematic review and meta-analysis
Background The COVID-19 has caused significant mortality and morbidity across the globe.
Patients with cancer are especially vulnerable given their immunocompromised state. We …
Patients with cancer are especially vulnerable given their immunocompromised state. We …