Nitrate contamination in drinking water and adverse reproductive and birth outcomes: a systematic review and meta-analysis

L Lin, S St Clair, GD Gamble, CA Crowther, L Dixon… - Scientific Reports, 2023 - nature.com
Exposure to low levels of nitrate in drinking water may have adverse reproductive effects.
We reviewed evidence about the association between nitrate in drinking water and adverse …

Prenatal Exposure to Nitrate in Drinking Water and Adverse Health Outcomes in the Offspring: a Review of Current Epidemiological Research

PJ Clemmensen, J Schullehner, N Brix… - Current Environmental …, 2023 - Springer
Abstract Purpose of Review Recently, several epidemiological studies have investigated
whether prenatal exposure to nitrate from drinking water may be harmful to the fetus, even at …

Danish water supply areas and their links to water production facilities: an open-access data set

J Schullehner - Geus Bulletin, 2022 - geusbulletin.org
This data set establishes the missing link between drinking-water quality monitoring data at
the water production facility level in the Danish national geodatabase Jupiter and supply …

Exposure to nitrosatable drugs during pregnancy and childhood cancer: A matched case–control study in Denmark, 1996–2016

A Sirirungreung, J Hansen, D He… - … and drug safety, 2023 - Wiley Online Library
Background Nitrosatable drugs can be synthesized to N‐nitroso compounds in human
stomach. In a pregnant woman, N‐nitroso compounds can be translocated to the fetus …

[HTML][HTML] Prenatal nitrate exposure from diet and drinking water and timing of puberty in sons and daughters: a nationwide cohort study

PJ Clemmensen, N Brix, J Schullehner… - Environment …, 2022 - Elsevier
Abstract Background In Western countries, age at pubertal development has declined during
the last century in girls, and probably also in boys. No studies have investigated whether …

Nitrate in drinking water and pregnancy outcomes: A narrative review of epidemiological evidence and proposed biological mechanisms

H Royal, A 't Mannetje, S Hales, J Douwes, M Berry… - PLOS water, 2024 - journals.plos.org
There is emerging evidence of an association between nitrate contamination in drinking
water and adverse pregnancy outcomes. Few studies have discussed the evidence in the …

[HTML][HTML] Prenatal exposure to nitrosatable drugs and timing of puberty in sons and daughters: A nationwide cohort study

PJ Clemmensen, N Brix, J Schullehner, A Ernst… - International Journal of …, 2023 - Elsevier
Background N-nitroso compounds (NOCs) can be formed by endogenous reactions
between nitrosatable drugs and nitrite. Animal studies have found that several NOCs are …

Maternal use of nitrosatable drugs during pregnancy and adult male reproductive health: A population‐based cohort study

PJ Clemmensen, N Brix, J Schullehner, G Toft… - …, 2024 - Wiley Online Library
Background Prenatal exposures to xenobiotics during the masculinization programming
window are suggested to impact male fecundity later in life. Frequently used nitrosatable …

Nitrate in drinking water and time to pregnancy or medically assisted reproduction in women and men: a nationwide cohort study in the Danish national birth cohort

NH Ebdrup, UB Knudsen, J Schullehner… - Clinical …, 2022 - Taylor & Francis
Purpose No studies have investigated if drinking water nitrate affects human fecundity.
Experimental studies point at detrimental effects on fetal development and on female and …

Perspectives on environment and health research in Denmark

HT Horsdal, MG Pedersen… - … journal of public …, 2023 - journals.sagepub.com
Aims: We provide an overview of nationwide environmental data available for Denmark and
its linkage potentials to individual-level records with the aim of promoting research on the …