Liposome and immune system interplay: Challenges and potentials

F Zahednezhad, M Saadat, H Valizadeh… - Journal of Controlled …, 2019 - Elsevier
Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

Nanotherapeutics relieve rheumatoid arthritis

M Yang, X Feng, J Ding, F Chang, X Chen - Journal of Controlled Release, 2017 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease associated with
persistent multiarticular synovitis, cartilage destruction, and even loss of joint function …

Pulmonary surfactant and drug delivery: Focusing on the role of surfactant proteins

R Guagliardo, J Perez-Gil, S De Smedt… - Journal of Controlled …, 2018 - Elsevier
Pulmonary surfactant (PS) has been extensively studied because of its primary role in
mammalian breathing. The deposition of this surface-active material at the alveolar air-water …

Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases

CF Anderson, ME Grimmett… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Respiratory illnesses are prevalent around the world, and inhalation‐based therapies
provide an attractive, noninvasive means of directly delivering therapeutic agents to their site …

[HTML][HTML] Formulation strategies for folate-targeted liposomes and their biomedical applications

P Kumar, P Huo, B Liu - Pharmaceutics, 2019 - mdpi.com
The folate receptor (FR) is a tumor-associated antigen that can bind with folic acid (FA) and
its conjugates with high affinity and ingests the bound molecules inside the cell via the …

Folate-targeted nanoparticles for rheumatoid arthritis therapy

E Nogueira, AC Gomes, A Preto… - … , Biology and Medicine, 2016 - Elsevier
Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease, affecting
almost 1% of the world population. Although the cause of RA remains unknown, the complex …

[HTML][HTML] Multifunctional lipid-based nanoparticles for codelivery of anticancer drugs and siRNA for treatment of non-small cell lung cancer with different level of …

J Majumder, T Minko - Pharmaceutics, 2021 - mdpi.com
Resistance to chemotherapy, enhanced proliferation, invasion, angiogenesis, and
metastasis (RPIAM) represent major obstacles that limit the efficacy of cancer treatment …

[HTML][HTML] Protective effect of saccharides on freeze-dried liposomes encapsulating drugs

D Guimarães, J Noro, C Silva… - … in bioengineering and …, 2019 - frontiersin.org
The production of freeze-dried liposomes encapsulating drugs is considered a key
challenge since the drugs are prone to leakage. The aim of this work was to study the effect …

[HTML][HTML] Increased encapsulation efficiency of methotrexate in liposomes for rheumatoid arthritis therapy

D Guimarães, J Noro, A Loureiro, F Lager, G Renault… - Biomedicines, 2020 - mdpi.com
Methotrexate (MTX) is a common drug used to treat rheumatoid arthritis. Due to the
excessive side effects, encapsulation of MTX in liposomes is considered an effective …

Biotechnological applications of mammalian odorant-binding proteins

F Gonçalves, A Ribeiro, C Silva… - Critical Reviews in …, 2021 - Taylor & Francis
The olfactory system of mammals allows the detection and discrimination of thousands of
odors from the environment. In mammals, odorant-binding proteins (OBPs) are considered …