[HTML][HTML] The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies
T Zhong, W Zhang, H Guo, X Pan, X Chen, Q He… - … Pharmaceutica Sinica B, 2022 - Elsevier
Transient receptor potential (TRP) channels are one primary type of calcium (Ca 2+)
permeable channels, and those relevant transmembrane and intracellular TRP channels …
permeable channels, and those relevant transmembrane and intracellular TRP channels …
Receptor tyrosine kinase signaling and targeting in glioblastoma multiforme
Glioblastoma multiforme (GBM) is amongst the deadliest of human cancers, with a median
survival rate of just over one year following diagnosis. Characterized by rapid proliferation …
survival rate of just over one year following diagnosis. Characterized by rapid proliferation …
Active constituents of saffron (Crocus sativus L.) and their prospects in treating neurodegenerative diseases
W Yang, X Qiu, Q Wu, F Chang… - Experimental and …, 2023 - spandidos-publications.com
Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …
TRP channels in cancer: signaling mechanisms and translational approaches
M Marini, M Titiz, D Souza Monteiro de Araújo… - Biomolecules, 2023 - mdpi.com
Ion channels play a crucial role in a wide range of biological processes, including cell cycle
regulation and cancer progression. In particular, the transient receptor potential (TRP) family …
regulation and cancer progression. In particular, the transient receptor potential (TRP) family …
Molecular pathways implicated in radioresistance of glioblastoma multiforme: what is the role of extracellular vesicles?
Glioblastoma multiforme (GBM) is a primary brain tumor that is very aggressive, resistant to
treatment, and characterized by a high degree of anaplasia and proliferation. Routine …
treatment, and characterized by a high degree of anaplasia and proliferation. Routine …
TUNAR lncRNA encodes a microprotein that regulates neural differentiation and neurite formation by modulating calcium dynamics
E Senís, M Esgleas, S Najas… - Frontiers in cell and …, 2021 - frontiersin.org
Long noncoding RNAs (lncRNAs) are regulatory molecules which have been traditionally
considered as “non-coding”. Strikingly, recent evidence has demonstrated that many non …
considered as “non-coding”. Strikingly, recent evidence has demonstrated that many non …
Subtype specific targeting of calcium signaling in breast cancer
An important component of breast milk, calcium also appears as radiographically prominent
microcalcifications in breast tissue that are often the earliest sign of malignancy. Ionic Ca 2+ …
microcalcifications in breast tissue that are often the earliest sign of malignancy. Ionic Ca 2+ …
Glioblastoma pharmacotherapy: A multifaceted perspective of conventional and emerging treatments
AS Sevastre, A Costachi… - Experimental and …, 2021 - spandidos-publications.com
Due to its localisation, rapid onset, high relapse rate and resistance to most currently
available treatment methods, glioblastoma multiforme (GBM) is considered to be the …
available treatment methods, glioblastoma multiforme (GBM) is considered to be the …
[HTML][HTML] Mitochondrial dysfunction and calcium dyshomeostasis in the pectoralis major muscle of broiler chickens with wooden breast myopathy
X Zhang, T Xing, J Li, L Zhang, F Gao - Poultry Science, 2023 - Elsevier
The incidence of wooden breast (WB) meat of commercial broiler chicken has been
increasing in recent years. Histological examination found that the occurrence of WB …
increasing in recent years. Histological examination found that the occurrence of WB …
A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma
S Luanpitpong, N Rodboon, P Samart… - British Journal of …, 2020 - nature.com
Background Calcium is an essential signal transduction element that has been associated
with aggressive behaviours in several cancers. Cell motility is a prerequisite for metastasis …
with aggressive behaviours in several cancers. Cell motility is a prerequisite for metastasis …