Comparative protein structure modeling of genes and genomes

MA Martí-Renom, AC Stuart, A Fiser… - Annual review of …, 2000 - annualreviews.org
▪ Abstract Comparative modeling predicts the three-dimensional structure of a given protein
sequence (target) based primarily on its alignment to one or more proteins of known …

Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements

AA Schäffer, L Aravind, TL Madden… - Nucleic acids …, 2001 - academic.oup.com
PSI-BLAST is an iterative program to search a database for proteins with distant similarity to
a query sequence. We investigated over a dozen modifications to the methods used in PSI …

The Dfam community resource of transposable element families, sequence models, and genome annotations

J Storer, R Hubley, J Rosen, TJ Wheeler, AF Smit - Mobile DNA, 2021 - Springer
Dfam is an open access database of repetitive DNA families, sequence models, and
genome annotations. The 3.0–3.3 releases of Dfam (https://dfam. org) represent an evolution …

Comparative protein structure modeling using MODELLER

B Webb, A Sali - Current protocols in bioinformatics, 2016 - Wiley Online Library
Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

Semi-Supervised Learning (Chapelle, O. et al., Eds.; 2006) [Book reviews]

O Chapelle, B Scholkopf, A Zien - IEEE Transactions on Neural …, 2009 - ieeexplore.ieee.org
This book addresses some theoretical aspects of semisupervised learning (SSL). The book
is organized as a collection of different contributions of authors who are experts on this topic …

Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world

L Parenicova, S De Folter, M Kieffer, DS Horner… - The Plant …, 2003 - academic.oup.com
MADS-box transcription factors are key regulators of several plant development processes.
Analysis of the complete Arabidopsis genome sequence revealed 107 genes encoding …

Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure

J Gough, K Karplus, R Hughey, C Chothia - Journal of molecular biology, 2001 - Elsevier
Of the sequence comparison methods, profile-based methods perform with greater
selectively than those that use pairwise comparisons. Of the profile methods, hidden Markov …

[图书][B] Kernel methods in computational biology

B Schölkopf, K Tsuda, JP Vert - 2004 - books.google.com
A detailed overview of current research in kernel methods and their application to
computational biology. Modern machine learning techniques are proving to be extremely …

Systematic identification of novel protein domain families associated with nuclear functions

T Doerks, RR Copley, J Schultz, CP Ponting… - Genome …, 2002 - genome.cshlp.org
A systematic computational analysis of protein sequences containing known nuclear
domains led to the identification of 28 novel domain families. This represents a 26 …

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

J Glanville, W Zhai, J Berka, D Telman… - Proceedings of the …, 2009 - National Acad Sciences
Antibody repertoire diversity, potentially as high as 1011 unique molecules in a single
individual, confounds characterization by conventional sequence analyses. In this study, we …