Practical recommendations for using ctDNA in clinical decision making

SA Cohen, MC Liu, A Aleshin - Nature, 2023 - nature.com
The continuous improvement in cancer care over the past decade has led to a gradual
decrease in cancer-related deaths. This is largely attributed to improved treatment and …

[HTML][HTML] Early stage colon cancer: Current treatment standards, evolving paradigms, and future directions

S Chakrabarti, CY Peterson, D Sriram… - World journal of …, 2020 - ncbi.nlm.nih.gov
Colon cancer continues to be one of the leading causes of mortality and morbidity
throughout the world despite the availability of reliable screening tools and effective …

Adjuvant therapy for stage II colon cancer: ASCO guideline update

NN Baxter, EB Kennedy, E Bergsland… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To develop recommendations for adjuvant therapy for patients with resected
stage II colon cancer. METHODS ASCO convened an Expert Panel to conduct a systematic …

Detection of microsatellite instability: state of the art and future applications in circulating tumour DNA (ctDNA)

P Gilson, JL Merlin, A Harlé - Cancers, 2021 - mdpi.com
Simple Summary Microsatellite instability (MSI) is a molecular fingerprint for defects in the
mismatch repair system (dMMR) and is associated with higher risks of cancers. MSI/dMMR …

Colorectal cancer liver metastases: Genomics and biomarkers with focus on local therapies

Y Kitsel, T Cooke, V Sotirchos, CT Sofocleous - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is a leading cause of death among cancer
patients, and the liver is the most common visceral metastatic site. Despite promising …

Biomarkers in metastatic colorectal cancer: status quo and future perspective

A Puccini, A Seeber, MD Berger - Cancers, 2022 - mdpi.com
Simple Summary Despite recent progress in the treatment of metastatic colorectal cancer
patients, novel therapeutic approaches are highly warranted to further improve outcome …

[HTML][HTML] Immunotherapy in microsatellite instability metastatic colorectal cancer: Current status and future perspectives

R Motta, S Cabezas-Camarero… - Journal of clinical and …, 2021 - ncbi.nlm.nih.gov
Background: Colorectal cancer (CRC) is one of the most frequent and deadly malignancies
worldwide. This specific pathology is composed of various molecular entities, with distinct …

Molecular subtyping in colorectal cancer: A bridge to personalized therapy

C Wang, H Zhang, Y Liu, Y Wang… - Oncology …, 2023 - spandidos-publications.com
Colorectal cancer (CRC) is a malignant tumor and a major cause of morbidity and mortality
globally. The classic Tumor‑Node‑Metastasis staging system, which currently underlies the …

[HTML][HTML] Clinical significance of MLH1/MSH2 for stage II/III sporadic colorectal cancer

SM Wang, B Jiang, Y Deng, SL Huang… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND The development of colorectal cancer (CRC) is a complicated multistep
process that involves an accumulation of mutations in tumor suppressor genes and …

Management of colorectal cancer in the era of COVID-19: Challenges and suggestions

W Alam, Y Bouferraa, Y Haibe, D Mukherji… - Science …, 2021 - journals.sagepub.com
The Coronavirus (COVID-19) pandemic had a huge impact on all sectors around the world.
In particular, the healthcare system has been subject to an enormous pressure that has …