Background Systemic antimicrobials can be used as an adjunct to mechanical debridement
(scaling and root planing (SRP)) as a non‐surgical treatment approach to manage …

The purpose of this study was to prepare poly (DL) lactide-co-glycolide (PLGA) and poly ε-
caprolactone (PCL) nanofibers containing metronidazole and amoxicillin using an …

Introduction Periodontitis is a biofilm-mediated disease that is usually treated by non-
surgical biofilm elimination with or without antibiotics. Antibiotic treatment in periodontal …

Background Many systematic reviews and meta-analysis have indicated beneficial effects of
adjunctive systemic antibiotics in periodontal therapy in specific situations. However, some …

Oxygen is an essential nutrient for cellular metabolism, especially energy production. The
substance is involved in multiple processes including oxidative killing of bacteria …

Periodontitis is a major public health problem, that can have local and systemic
consequences ranging from tooth loss to the aggravation of other chronic diseases. The …

Aim To evaluate the frequency of side effects associated with intake of metronidazole
(MTZ)+ amoxicillin (AMX) in periodontal treatment, and to explore associations between …

The mechanosensitivity of inflammation can alter cellular mechanotransduction. However,
the underlying mechanism remains unclear. This study aims to investigate the metabolic …

Objective To evaluate the effect of the periodontal treatment on Aggregatibacter
actinomycetemcomitans JP2 clone, and the IgG serum levels against its outer membrane …

Introduction Quorum-quenching enzyme Est816 hydrolyzes the lactone rings of N-acyl
homoserine lactones, effectively blocking the biofilm formation and development of Gram …