[HTML][HTML] Current principles of motor control, with special reference to vertebrate locomotion

S Grillner, A El Manira - Physiological reviews, 2019 - journals.physiology.org
The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

The neural control of interlimb coordination during mammalian locomotion

A Frigon - Journal of neurophysiology, 2017 - journals.physiology.org
Neuronal networks within the spinal cord directly control rhythmic movements of the
arms/forelimbs and legs/hindlimbs during locomotion in mammals. For an effective …

[HTML][HTML] Computational modeling of spinal circuits controlling limb coordination and gaits in quadrupeds

SM Danner, NA Shevtsova, A Frigon, IA Rybak - Elife, 2017 - elifesciences.org
Interactions between cervical and lumbar spinal circuits are mediated by long propriospinal
neurons (LPNs). Ablation of descending LPNs in mice disturbs left-right coordination at high …

Distinguishing subtypes of spinal locomotor neurons to inform circuit function and dysfunction

KJ Dougherty - Current Opinion in Neurobiology, 2023 - Elsevier
Locomotion is a complex motor task executed by spinal neurons. Given the diversity of
spinal cord neurons, linking neuronal cell type to function is a challenge. Molecular …

State-dependent rhythmogenesis and frequency control in a half-center locomotor CPG

J Ausborn, AC Snyder, NA Shevtsova… - Journal of …, 2018 - journals.physiology.org
The spinal locomotor central pattern generator (CPG) generates rhythmic activity with
alternating flexion and extension phases. This rhythmic pattern is likely to result from …

[HTML][HTML] Computational modeling of brainstem circuits controlling locomotor frequency and gait

J Ausborn, NA Shevtsova, V Caggiano, SM Danner… - Elife, 2019 - elifesciences.org
A series of recent studies identified key structures in the mesencephalic locomotor region
and the caudal brainstem of mice involved in the initiation and control of slow (exploratory) …

The role of V3 neurons in speed-dependent interlimb coordination during locomotion in mice

H Zhang, NA Shevtsova, D Deska-Gauthier, C Mackay… - Elife, 2022 - elifesciences.org
Speed-dependent interlimb coordination allows animals to maintain stable locomotion
under different circumstances. The V3 neurons are known to be involved in interlimb …

[HTML][HTML] Spinal interneurons: diversity and connectivity in motor control

M Sengupta, MW Bagnall - Annual Review of Neuroscience, 2023 - annualreviews.org
The spinal cord is home to the intrinsic networks for locomotion. An animal in which the
spinal cord has been fully severed from the brain can still produce rhythmic, patterned …

[HTML][HTML] Spinal inhibitory interneurons: gatekeepers of sensorimotor pathways

NJ Stachowski, KJ Dougherty - International journal of molecular sciences, 2021 - mdpi.com
The ability to sense and move within an environment are complex functions necessary for
the survival of nearly all species. The spinal cord is both the initial entry site for peripheral …

[HTML][HTML] Spinal cords: Symphonies of interneurons across species

AC Wilson, LB Sweeney - Frontiers in Neural Circuits, 2023 - frontiersin.org
Vertebrate movement is orchestrated by spinal inter-and motor neurons that, together with
sensory and cognitive input, produce dynamic motor behaviors. These behaviors vary from …