Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine

LE Pomeranz, AE Reynolds… - … and molecular biology …, 2005 - Am Soc Microbiol
Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …

Cell biological and molecular characteristics of pseudorabies virus infections in cell cultures and in pigs with emphasis on the respiratory tract

H Nauwynck, S Glorieux, H Favoreel, M Pensaert - Veterinary research, 2007 - hal.science
In the present review, several cell biological and molecular aspects of virus-cell and virus-
host (pig) interactions are reviewed for pseudorabies (Aujeszky's disease) virus. Concerning …

The antiviral activity of kaempferol against pseudorabies virus in mice

L Li, R Wang, H Hu, X Chen, Z Yin, X Liang, C He… - BMC veterinary …, 2021 - Springer
Background Pseudorabies virus (PRV), a member of the Alphaherpesviruses, is one of the
most important pathogens that harm the global pig industry. Accumulated evidence …

Proteomic characterization of pseudorabies virus extracellular virions

T Kramer, TM Greco, LW Enquist, IM Cristea - Journal of virology, 2011 - Am Soc Microbiol
Pseudorabies virus (PRV), a member of the Alphaherpesvirinae, has a complex multilayered
extracellular virion that is structurally conserved among other herpesviruses. PRV virions …

Membrane fusion, potential threats, and natural antiviral drugs of pseudorabies virus

N Ye, W Feng, T Fu, D Tang, Z Zeng, B Wang - Veterinary Research, 2023 - Springer
Pseudorabies virus (PrV) can infect several animals and causes severe economic losses in
the swine industry. Recently, human encephalitis or endophthalmitis caused by PrV infection …

Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins

RD Everett, C Boutell, C McNair, L Grant… - Journal of virology, 2010 - Am Soc Microbiol
Immediate-early protein ICP0 of herpes simplex virus type 1 (HSV-1) is an E3 ubiquitin
ligase of the RING finger class that is required for efficient lytic infection and reactivation from …

Suppression of the interferon-mediated innate immune response by pseudorabies virus

A Brukman, LW Enquist - Journal of virology, 2006 - Am Soc Microbiol
Pseudorabies virus (PRV) is an alphaherpesvirus related to the human pathogens herpes
simplex virus type 1 (HSV-1) and varicella-zoster virus. PRV is capable of infecting and …

Advances in the immunoescape mechanisms exploited by alphaherpesviruses

Y Wang, C Ma, S Wang, H Wu, X Chen, J Ma… - Frontiers in …, 2024 - frontiersin.org
Alphaherpesviruses, categorized as viruses with linear DNA composed of two
complementary strands, can potentially to induce diseases in both humans and animals as …

Pseudorabies virus EP0 protein counteracts an interferon-induced antiviral state in a species-specific manner

A Brukman, LW Enquist - Journal of virology, 2006 - Am Soc Microbiol
Pseudorabies virus (PRV), an alphaherpesvirus related to herpes simplex virus type 1 and
varicella-zoster virus, infects a broad host range of mammals. A striking characteristic of PRV …

Identification and characterization of G-quadruplex formation within the EP0 promoter of pseudorabies virus

JN Kong, C Zhang, YC Zhu, K Zhong, J Wang… - Scientific reports, 2018 - nature.com
EP0 is an important early gene that modulates the life cycle of pseudorabies virus (PRV). A
guanine-rich sequence overlapping with three Sp1 binding sites is located upstream of the …